虽然PMN的mCD14水平较低,但其胞内CD14 mRNA水平仍较高,PMN受细胞因子、趋化因子刺激时,其表面mCD14表达可明显增加。此外,非髓样细胞(non-myeloidcells)如B细胞、乳腺细胞也能表达很弱的mCD14。
[3] Wright S, Ramos R, Tobias P,et al. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein [J]. Science, 1990, 249(4975): 1431-1433. [4] Frey E A, Miller D S, Jahr T G,et al. Soluble CD14 participates in the response of cells to lipopolysacchari...
此外,已经表明 CD14 在细胞外空间捕获内源性脂质 DAMP,例如 oxPAPC,并将它们转运到内体中,导致树突状细胞的炎症小体活化和过度活化(By capturing inflammatory lipids released from dying cells, the receptor CD14 induces inflammasome-dependent phagocyte hyperactivation. Immunity)。因此,直接捕获宿主和微生物来源的...
IPHASE Human Peripheral Blood CD14+ Cells 产品名称:人外周血单核细胞(CD14+) 组织来源:人外周血(PB) 供体状态:健康 血液抗凝剂:肝素钠 纯度:单核细胞(CD14+)的纯度为≥85% (流式细胞仪检测) 产品规格:20 million Frozen,1mL/管 储存条件:液氮冻存 ...
Endothelial-like cells derived from human CD14 positive monocytes. Differentiation . 2000; 65 : 287-300.Fernandez Pujol B, Lucibello FC, Gehling UM, Lindemann K, Weidner N, et al. Endothelial-like cells derived from human CD14 positive monocytes. Differentiation. 2000; 65 :287–300....
中性粒细胞(PMN)也能表达CD14,但其数量较单核细胞表面CD14少近10倍。虽然PMN的mCD14水平较低,但其胞内CD14 mRNA水平仍较高,PMN受细胞因子、趋化因子刺激时,其表面mCD14表达可明显增加。此外,非髓样细胞(non-myeloidcells)如B细胞、乳腺细胞也能表达很弱的mCD14。
CD14+cells with phenotype of M2 macrophages had high phagocytic activity for monosodium urate crystals. Thus, our results indicate that monocytes/macrophages from patients with gout have the phenotype of infiltrated monocytes, and these cells consist of different populations characterized by anti-...
The rostral migratory stream consists of a large number of cells migrating from the lateral ventricles to the rostral telencephalon, primarily the olfactory bulb. The pathway continually provides neuro- and glioblasts throughout life. The present paper indicates that a considerable number of cells und...
We used flow cytometry to identify the presence of intracellular cytokines (cytoflow) and analyse the production of IL-4 in peripheral blood from AIDS patients who have practically no CD4+ T cells. We found that IL-4 was produced by CD3−CD4−CD8−CD56−CD19−CD14− cells and CD3...
E.G7-OVA(小鼠T细胞) 5×106cells/瓶×2 磷酸钠(pNPP)磷酸酶检测试剂盒pNPP influenza B virus nucleoprotein B核蛋白单*抗体规格: 0.1ml IFABP 小肠型脂肪酸结合蛋白抗体规格: 0.2ml IFABP 小肠型脂肪酸结合蛋白抗体规格: 0.2ml IFI16/p16 γ干扰素诱导蛋白16抗体规格: 0.1ml ...