Cellular immune responses: CD107a expression by CD4 T cells and granzyme B production by CD8 T cells.doi:10.1371/journal.pone.0112910.g006M. ElseSchats RemkoM. JoshuaC. B. Marijevan Gemert Geert-Janvan de Vegte-Bolmer MargaG. Wouter...
(LAMP-1) and is widely expressed intracellular antigen. It can be found on the surface of PHA-activated lymphocytes, activated platelets, cytotoxic T cells, NK cells, macrophages, epithelial cells, endothelial cells, and some tumor lines. CD107a is a ligand for E-selectin and galaptin and ...
Results: Flow cytometry analyses revealed that NKT cells are the major CD107a-expressing cell population committed to cytotoxicity in CL lesion, although we also observed high frequencies of CD4+ and DN T cells expressing CD107a. Analysing the pool of CD107a+-cell populations, we found a ...
(2014) Vaccine-induced CD107a+ CD4+ T cells are resistant to depletion following AIDS virus infection. J Virol 88: 14232-14240.Terahara, K., Ishii, H., Nomura, T., Takahashi, N., Takeda, A., Shiino, T., Tsunetsugu-Yokota, Y. & Matano, T. (2014). Vaccine-induced CD107a+ ...
Theurich S, Malcher J, Becker HJ, Chemnitz JM, Liebig TM, Shimabukuro- Vornhagen A, et al. Activated primary human B cells efficiently induce early CD40L and CD107a expression in CD4+ T cells. Blood 2011;118:5979-80.Theurich S, Malcher J, Becker HJ, et al. Activated primary human ...
Naito T, Baba T, Takeda K, Sasaki S, Nakamoto Y, Mukaida N. High-dose cyclophosphamide induces specific tumor immunity with concomitant recruitment of LAMP1/CD107a-expressing CD4-positive T cells into tumor sites. Cancer Lett. 2015 Sep 28;366(1):93-9....
results in the transient surface expression of CD107a and CD107b (lysosomal associated membrane proteins).3 A protocol for the ex vivo assessment of antigen-specific cytokine production by mouse CD4+ and CD8+ T lymphocytes, and the simultaneous presence of CD107a and CD107b, by polychromatic ...
We define irreversible alterations of IRs co-expression patterns in CD8 T cells not mitigated by ART and identify negative associations between the frequency of TIGIT and TIGIT TIM-3 and CD4 T-cell levels. Moreover, changes in total, SEBactivated, and HIV-1-specific CD8...