用益生菌治疗减轻了OVA诱导的小鼠过敏症状。流式细胞术分析显示口服益生菌诱导粘膜CD103+树突细胞(DCs),其促进调节性T细胞(Tregs)的分化。 16S rRNA分析显示,益生菌调节了微生物群的组成,特别是通过增加递推杆菌和疣状体菌门的比例,以及增加粘液杆菌和梭菌属的比例,进而调节免疫系统。 该研究结果提供了应用益生菌...
DCs expressing CD103 (also known asCd, D CDc, PreimprintedNaive, D CPrimed, D CMesenteric, MedullaCcr, Primed
在主要组织相容性复合物I(MHCI)分子的背景下,T细胞由专业抗原呈递树突状细胞(DCS)在引流淋巴结中致敏。 前体记忆T细胞在促炎细胞因子(如I型干扰素)的影响下,进入肿瘤部位并进一步成熟。一群记忆前体细胞将进一步分化为CD103 CD69组织驻留记忆T(TRM)细胞。 与位于肿瘤微环境中的其他T细胞不同,TRM细胞保留在肿瘤组织...
技术领域:,具体涉及树突状细胞子集cd103+dc的体外培养方法及鉴定方法。背景技术::树突状细胞(dendriticcells,dcs)是目前所知功能最强的专职抗原提呈细胞,能高效地摄取、加工和提呈抗原。未成熟的dc具有较强的迁移能力,成熟的dc表面会形成树突样结构,它可刺激幼稚t细胞和b细胞的分化,在调节天然免疫与获得性免疫维持机体...
ARTICLES nature publishing group See COMMENTARY page XX Intestinal CD103− dendritic cells migrate in lymph and prime effector T cells V Cerovic1, SA Houston1, CL Scott1, A Aumeunier1, U Yrlid2, AM Mowat1 and SWF Milling1 Intestinal dendritic cells (DCs) continuously migrate through ...
货号16-1031-82 CNY2,284.00 查看价格 下单后预计有货时间 08-Jan-2025 数量 批量或定制请求 性能保障 说明书 实验方案 技术支持 已发表图片 (19) Application Created with Sketch. 图:1/19 CD103 (Integrin alpha E) Antibody (16-1031-82) in IHC ...
CD103+CD11b+ dendritic cells (DCs) are unique to the intestine, but the factors governing their differentiation are unclear. Here we show that transforming growth factor receptor 1 (TGFβR1) has an indispensable, cell intrinsic role in the development of
REVIEW nature publishing group CD103+ GALT DCs promote Foxp3+ regulatory T cells KRR Siddiqui1 and F Powrie1 There is evidence that Foxp3+ regulatory T (TR) cells contribute to intestinal homeostasis and that deficiencies in this population can lead to chronic intestinal inflammation. Here, we...
ARTICLES nature publishing group See ARTICLE page 658 See ARTICLE page 670 Loss of mucosal CD103 + DCs and IL-17 + and IL-22 + lymphocytes is associated with mucosal damage in SIV infection NR Klatt1, JD Estes2, X Sun3, AM Ortiz4,5, JS Barber6, LD Harris1, B Cervasi4, LK ...
目的:探索小鼠骨髓单个核细胞在体外培养诱导其分化为CD103~+树突状细胞(DCs)的方法,为免疫性疾病的防治提供实验基础.方法:分离小鼠胫腓骨,冲洗骨髓腔得到骨髓细胞,利用单个核细胞分离液分离出单个核细胞,加入粒细胞巨噬细胞集落刺激因子(GM-CSF),Fms样酪氨酸激酶3配体(FLT3L)诱导其分化为成熟的DCs.显微镜下观察细胞...