CD103+ DC is crucial for antitumor immune response. As a promising local therapy on cancers, nanosecond pulsed electric field (nsPEF) has been widely reported to stimulate anti-tumor immune response, but the un
首先,在CD130+DC中发现,SA-TL能够显著上调STING下游蛋白pTBK1、诱导I型干扰素的产生并促进DC的活化,说明STING激动剂脂质体在体外具有免疫刺激能力。接着,作者在“热”肿瘤MC38皮下瘤模型中探究这种靶向脂质体的抗肿瘤效果,如图1所示,4...
中图分类号: S 852.42 文献标志码:A 文章编号: 1673 - 4696 (2015 ) 08 - 0843 - 05CD11c+DC和CD103+DC及CD68+M φ 在双峰驼肠系膜淋巴结中的分布特点李淑娴,郭明刚,张学锋,曹婷婷,刘 磊,范希萍,王雯慧 *(甘肃农业大学 动物医学院,甘肃 兰州 730070 ) 摘要:为了探讨 CD11c和 CD103分子标记物标记的树...
树突状细胞(dc)能诱导肠道对摄入蛋白质抗原产生耐受性,这是提高T cells免疫的一部分。固有层(LP)在大量的吸收绒毛状上皮细胞之下,吸收细胞包含大量的树突状细胞(CD11c+CD11b+MHCII+cells)主要由CD103+CX3CR1- DCs两个组成,它能促进IgA生产、印在肠道淋巴细胞上和调节T细胞的发展。CX3CR1 +、CD103 -DCs(...
The CD103+CD11bDC subset has gained a functional specialization that able them to repress inflammation via several epithelial interferon-γ (IFN-γ)-induced proteins. Among others, we identified that epithelial IDO1 and interleukin-18-binding protein (IL-18bp) were strongly modulated by CD103+CD...
Here we demonstrate, for the first time, the presence of two distinct CD103− DC subsets in intestinal lymph. Similar to CD103+ DCs, these intestine-derived CD103− DCs are responsive to Flt3 and they efficiently prime and confer a gut-homing phenotype to naive T cells. However, ...
近日,国际权威学术期刊《Hepatology》在线发表了上海交通大学医学院附属仁济医院马雄教授课题组的原创性研究论文。该研究首次报道衣康酸可以通过抑制CD103+组织驻留记忆性T细胞(tissue resident memory T cells, TRM)的诱导和效应功能,有效缓解...
关于CD103+ DC的叙述正确的是 ()A.诱导初始T细胞向Thl7细胞分化B.可产生维甲酸C.可诱导黏膜B细胞向IgA进行类别转换D.诱导初始T细胞向Treg细胞分化E.可产生TGF-β的答案是什么.用刷刷题APP,拍照搜索答疑.刷刷题(shuashuati.com)是专业的大学职业搜题找答案,刷题练习的工具
树突状细胞(dc)能诱导肠道对摄入蛋白质抗原产生耐受性,这是提高T cells免疫的一部分。固有层(LP)在大量的吸收绒毛状上皮细胞之下，吸收细胞包含大量的树突状细胞(CD11c+CD11b+MHCII+cells)主要由CD103+CX3CR1- DCs两个组成,它能促进IgA生产、印在肠道淋巴细胞上和调节T细胞的发展。CX3CR1 + 、CD103 - DCs...
nature publishing group ARTICLES OPEN CCR2 þ CD103 À intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells CL Scott1,2, CC Bain1, PB Wright1, D Sichien2, K Kotarsky3, EK Persson3, K Luda3, M Guilliams2, BN Lambrecht2, WW...