A marked up-regulation of CCL5 and in particular the receptor CCR1 with strict dependence on cell–cell contacts and culture dimensionality was evident. Furthermore, the impact of direct contacts between ASCs and tumor cells and the involvement of CCR1 in promoting tumor cell...
Xiao Hu ZhangJie Ting ZhangSien LinLiang Liang XuBiao HuangFu Yuan YangHai Long LiuBin WangStem Cell ReportsEpigenetic Modification of the CCL5/CCR1/ERK Axis Enhances Glioma Targeting in Dedifferentiation-Reprogra mmed BMSCs. Chen R,Lee WY,Zhang XH,et al. Stem Cell Reports . 2017...
Pretreatment of macrophages with an antagonist of CCR1, the primary receptor for CCL3 and CCL4, blocked cytokine-mediated migration. Conclusion Our findings indicate that TNFα and IL-1β modulate the expression of CCL3 in NP cells by controlling the activation of MAPK, NF-κB, and C/EBPβ...
Pham, K., et al., CCL5, CCR1 and CCR5 in murine glioblastoma: immune cell infiltra‐ tion and survival rates are not dependent on individual expression of either CCR1 or CCR5. J Neuroimmunol, 2012. 246(1-2): 10-7.Pham K, Luo D, Liu C, et al. CCL5, CCR1 and CCR5 in murine...
CC chemokine receptor 1 (CCR1); CCR5; chemokine C-C motif ligand 5 (RANTES; CCL5)Studies in humans, in mice and in cell culture suggest that targeting CCR1 and CCR5 could help treat liver fibrosis.Science-Business eXchangedoi:10.1038/scibx.2009.975None...
The chemokine CCL5 induces CCR1-mediated hyperalgesia in mice inoculated with NCTC 2472 tumoral cells. Neuroscience. 2014; 259 :113–125.Pevida M, Lastra A, Meana A, Hidalgo A, Baamonde A, Menendez L: The chemokine CCL5 induces CCR1-mediated hyperalgesia in mice inoculated with NCTC 2472 ...
RNA sequencing of OM-Mac蠁 and microarray study of BMDM revealed that CCL6 deletion produces enhanced TGF尾1+CSF-1+CCL5+ expression in OM-Mac蠁 and an increase in TGF尾1+CSF-1+CCL9+ in BMDM. This acts as a rescue mechanism to maintain activation of their shared CCR1 receptor with a...
CCR1 blockade inhibits both CCL5/RANTES- and SF-induced RA monocyte migration (A) RA monocyte migration induced by CCL5/RANTES and blocked by anti-CCR1 antibody.Maria C. LebreClarissa E. VergunstIvy Y. K. ChoiSaïda ...
CCL5/CCR1 axis regulates multipotency of human adipose tissue derived stromal cells. Stem Cell Res 2013; 10: 166-178.Kauts M-L, Pihelgas S, Orro K, Neuman T, Piirsoo A: CCL5/CCR1 axis regulates multipotency of human adipose tissue derived stromal cells. Stem Cell Res 2013, 10(2)...
( 2013 ). CCR1/CCL5 interaction promotes invasion of taxane-resistant PC3 prostate cancer cells by increasing secretion of MMPs 2/9 and by activating ERK and Rac signaling . Cytokine 64 : 251 – 257 .T. Kato, Y. Fujita, K. Nakane et al., "CCR1/CCL5 interaction promotes invasion of...