1mg期货 原价:¥19,999.90 +- 大包装询价添加到收藏夹比较DATASHEET 查看相关系列 CCR1 Agonist (15)CCR5 Agonist (16)所有研究领域 Skip to the end of the images gallery Skip to the beginning of the images gallery 基本描述 产品名称CCL3, CCR1 激动剂;CCR5 激动剂 ...
Essential contribution of a chemokine, CCL3, and its receptor, CCR1, to hepatocellular carcinoma progression. Int. J. Cancer 118:1869-1876.Yang X, Lu P, Ishida Y, et al . Essential contribution of achemo- kine, CCI3, and its receptor, CCR1, to hepatocellular carcinoma progression[J]. ...
目的:研究桑杏清营汤通过调控放射性肺损伤趋化因子CCL3/CCR1通路产生疗效的作用机制,为临床治疗放射性肺损伤提供新的治疗思路,也为进一步从伏气温病角度研究放射性肺损伤提供实验依据。方法:采用直线加速器6MV-X线(照距SSD为1m,剂量率为200cGy/min)对SD大鼠进行放射性肺损伤造模;病理观察桑杏清营汤对RILI模型大鼠...
CCL3/MIP-1␣ is pro-inflammatory in murine T cell-mediated hepatitis by recruiting CCR1-expressing CD4ϩ T cells to the liver. Eur. J. Immunol. 34:2907.Ajuebor, M. N., C. M. Hogaboam, T. Le, A. E. Proudfoot, and M. G. Swain. 2004. CCL3/MIP-1alpha is pro-...
We demonstrate a novel pro-inflammatory role for CCL3/MIP-1α since CCL3/MIP-1α deficiency significantly attenuated hepatic injury, both biochemically and histologically. Moreover, the recruitment of CCR1-expressing CD4+ T cells to the liver after Con A treatment was strikingly attenuated ...
CCL3/CCR1 axisCD14(+)CD16(−)knee osteoarthritismonocytesObjectives: Monocyte-derived macrophages, as the predominant immune cell type that is increased in inflamed synovium, play a vital role during knee osteoarthritis (KOA) progression. However, the mechanisms underlying the recruitment of ...
CCL3/CCR1 axisCCL2/CCR2 axisCD14(+)CD16(-)MonocytesKnee osteoarthritisObjectives: Monocyte-derived macrophages, as the predominant immune cell type that is increased in inflamed synovium, play a vital role during knee osteoarthritis (KOA) progression. However, the mechanisms underlying the ...
Pretreatment of macrophages with an antagonist of CCR1, the primary receptor for CCL3 and CCL4, blocked cytokine-mediated migration. Conclusion Our findings indicate that TNFα and IL-1β modulate the expression of CCL3 in NP cells by controlling the activation of MAPK, NF-κB, and C/EBPβ...
G. (2004). CCL3/MIP-1alpha is pro-inflammatory in murine T cell-mediated hepatitis by recruiting CCR1-expressing CD4(+) T cells to the liver. Eur. J. Immunol. 34, 2907-2918. :Ajuebor, M.N.; Hogaboam, C.M.; Le, T.; Proudfoot, A.E.; Swain, M.G. CCL...
CCR1 receptor antagonists; inhibitors of MIP-1 alpha (CCL3) binding to its receptor CCR1 found on inflammatory and immunomodulatory cells; macrophage inflammatory protein (MIP)doi:US6974817 B2A compound of the formula or the pharmaceutically acceptable salt thereof; wherein X, Y, a, b, c, d...