(Cbl-b-IN-10,Cbl-b-IN-10) 中文名称: Cbl-b-IN-10 英文名称: Cbl-b-IN-10 CAS No.: 2815225-12-6 分子式: C31H37F3N6O 分子量: 566.66029715538 如需查看该化合物的详细结构式,mol文件,smile,InChi 请点击:Cbl-b-IN-10结构式 下载该化合物MOL文件: Cbl-b-IN-10MOL PubChem CID: 16486920...
CBL-Bi's impact on potential substrates of CBL-B's E3 ligase activity was monitored for changes in treated human PBMCs using flow cytometry. Results When comparing Jurkat cells treated with anti-CD3 to those treated with anti-CD3 and CBL-Bi, significant differences were observed in tyrosine, ...
TargetMol Cbl-b-IN-3是一种有效的casitas b 系淋巴瘤原癌基因-b (Cbl-b)抑制剂(ic50 < 1 nM)。Cbl-b 是一种环型E3泛素蛋白连接酶,与T 淋巴细胞激活阈值的设定有关。Cbl-b 以不依赖于蛋白水解的方式负调控p85,通过其E3泛素连接酶活性,参与了p85向CD28和T 细胞抗原受体ζ的募集,抑制PI3K 抑制了Cblb-/...
英文名称 Cbl-b-IN-1 生化机理 Cbl-b-IN-1(例 519)是一种 Cbl-b 抑制剂,摘自专利 WO2019148005A1,IC 50 <100 nM。 储存温度 -20°C储存 运输条件 超低温冰袋运输 产品介绍 Cbl-b-IN-1 (example 519) is a Cbl-b inhibitor, extracted from patent WO2019148005A1, with an IC 50 <100 nM...
规格或纯度 10mM in DMSO 英文名称 Cbl-b-IN-1 生化机理 Cbl-b-IN-1(例 519)是一种 Cbl-b 抑制剂,摘自专利 WO2019148005A1,IC 50 <100 nM。 储存温度 -80℃储存 运输条件 超低温冰袋运输 产品介绍 Cbl-b-IN-1 (example 519) is a Cbl-b inhibitor, extracted from patent WO2019148005A1,...
Genetic studies indicate that Cbl and Cbl-b, two highly homologous adaptor proteins, are involved in the negative regulation of thymocyte development and peripheral T-cell activation, respectively. The recent identification of Cbl proteins as RING-type E3 ubiquitin ligases might provide insights into ...
中文名:CBL-B-IN-1,英文名:2-Pyridinecarboxamide, 4-(5-azaspiro[2.4]hept-5-ylmethyl)-6-cyclopropyl-N-[3-[3-[(4-methyl-4H-1,2,4-triazol-3-yl)methyl]-3-oxetanyl]phenyl]-,CAS:2368841-84-1,化学式:C29H34N6O2,分子量:498.62,MSDS.
Cbl-b-IN-3是一种有效的casitas b 系淋巴瘤原癌基因-b (Cbl-b)抑制剂(ic50 < 1 nM)。Cbl-b 是一种环型E3泛素蛋白连接酶,与T 淋巴细胞激活阈值的设定有关。Cbl-b 以不依赖于蛋白水解的方式负调控p85,通过其E3泛素连接酶活性,参与了p85向CD28和T 细胞抗原受体ζ的募集,抑制PI3K 抑制了Cblb-/- t 细胞...
protein kinase 9, interacts with calcium sensor calcineurin B-like protein 3 and regulates potassium homeostasis under low-potassium stress in Arabidopsis. Pla... LL Liu,HM Ren,LQ Chen,... - 《Plant Physiology》 被引量: 108发表: 2013年 SCABP8/CBL10, a putative calcium sensor, interacts wit...
T cell-intrinsic transforming growth factor β (TGFβ) receptor signaling plays an essential role in controlling immune responses. The RING-type E3 ligase Cbl-b has been shown to mediate the sensitivity of T cells to TGFβ; however, the mechanism underlying this process is unknown. This study...