【答案】:Caspase活化的DNA酶(Caspase activated DNase,CAD):通常情况下与其抑制因子ICAD结合处于失活状态。细胞凋亡程序启动后,活化的Caspase-3降解ICAD,使CAD释放出来并在核小体间切割DNA,形成间隔200bp或其整倍数的DNA片段。 已赞过 你对这个回答的评价是? 评论 收起 为你推荐:下载百度知道APP,抢鲜体验 使用百...
McGrath LB, Onnis V, Campiani G, Williams DC, Zisterer DM and McGee MM: Caspase-activated DNase (CAD)-independent oligonucleosomal DNA fragmentation in chronic myeloid leukaemia cells; a requirement for serine protease and Mn2+- dependent acidic endonuclease activity. Apoptosis 11: 1473-...
建议收到CAD (Caspase Activated Dnase) BioAssay ELISA Kit (Mouse)产品后将其置于4°C/-20°C保存。 其他 Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、...
人半胱天冬酶活化 DNase (CAD) ELISA试剂盒(Human Caspase Activated DNase (CAD) ELISA Kit)适用样本类型tissue homogenates and other biological fluids. 产品特点 试剂盒检测范围0.156-10ng/mL 保存建议 该人半胱天冬酶活化 DNase (CAD) ELISA试剂盒保存建议具体详情查看Reddot Biotech厂家提供的产品说明书。
研究背景:动脉粥样硬化是一种与炎症反应和巨噬细胞凋亡密切相关的慢性疾病,在晚期病变中,能导致继发性坏死和促炎反应的发生.Caspase激活的DNA酶(Caspase-activated Dnase,CAD)亦称为 DNA 裂解因子 40(DNA fragmentation factor 40,DFF40),是在细胞凋亡过程中引起DNA发生片段化的一种双链特异性核酸内切酶.已有研究报道...
MBS263269 |;猪Caspase激活的DNase(CAD)ELISA试剂盒尺寸:48条条状井| 目录号MBS263269 供应商Mybiosource 价格 尺寸48条条状井 基因targetCaspase激活的DNase CAD 简称猪Caspase-Activated DNase(CAD)ELISA试剂盒 简称猪Caspase-Activated DNase(CAD)酶联免疫吸附试验试剂盒 联系我们询问ELISA试剂盒,ELISA-Caspase-Activat...
Here, we examined whether caspase-activated DNase (CAD) is responsible for the DNA fragmentation that occurs upon exposure to various apoptotic stimuli. When human Jurkat cells were exposed to etoposide, or UV or gamma radiation, a caspase-3-like protease was activated, and nuclear DNA was ...
CAD (caspase-activated DNase) that causes chromosomal DNA fragmentation during apoptosis exists as a complex with ICAD (inhibitor of CAD) in proliferating cells. Here, we report that denatured CAD is functionally refolded with Hsc70-Hsp40 and ICAD. Hsc70-Hsp40 suppresses the aggregation of the ...
CADAlu repetitive elementshepatomaTherepetitive elements, which constitute 10% of human genome, may serve as bridges for genomic recombination. However, their roles in tumorigenesis remain to be elucidated. Caspase-activated DNase (CAD), whose gene () is mapped at chromosome 1p36, a region ...
Anti-ICAD(Inhibitor of Caspase-Activated Dnase )??Caspase 激活的脱氧核糖核酸酶抑制剂 价格: 价格电议 产品详情: Anti-ICAD(Inhibitor of Caspase-Activated Dnase )??Caspase 的脱氧核糖核酸酶剂抗原常规性能介绍 ... 纯度:99% 用途:仅限科研实验 不得用于临床医疗 品牌:欣维宇 产地:上海 是否进口:否 ant...