Apoptosis PathwayJoza et al deleted exon 3 of the aif gene in mouse embryonic stem (ES) cells. This exon encodes the amino terminus of the protein, and because the aif gene is on the X chromosome, mutation of one aif allele resulted in a complete knockout in male ES cells. The ...
NF-κB signaling blocks NLRC4/caspase-8-dependent apoptosis pathway.Casp1−/−Casp11−/−BMDMs were pre-stimulated for with or without various stimuli – Pam3CSK4 (1 μg ml−1), LPS (1 μg ml−1), R837 (2 μg ml−1), TNFα (100 ng ml−1), IFN-α (1...
细胞凋亡被认为是细胞更新,免疫系统的发育和功能,激素依赖性萎缩,胚胎发育和化学诱导细胞死亡等过程的重要组成部分。 Apoptosis is the process of programmed cell death characterized by distinct morphological characteristics and energy dependent biochemical mechanisms. Apoptosis is considered a vital component of pro...
6. L SW, Lee CH, Lin MS, et al. ZnO Nanoparticles Induced Caspase-Dependent Apoptosis in Gingival Squamous Cell Carcinoma through Mitochondrial Dysfunction and p70S6K Signaling Pathway. Int J Mol Sci. 2020, 21(5): 1612. 7. Gu HZ, Lin RR, Wang HC, et al. Effect of Momordica charantia...
After treatment of tanshinone IIA, caspase dependent apoptosis is observed in the osteosarcoma MG-63 cell line (including caspase-3, caspase-8, and caspase-9) [40], BT-20 human breast cancer cell line (including caspase-12, caspase-3) [41], 786-O human renal cell carcinoma cells (caspase...
参考细胞死亡命名委员会(NCCD)的分类,细胞死亡方式包括:内源性细胞凋亡(Intrinsic apoptosis)、外源性细胞凋亡(Extrinsic apoptosis)、坏死性凋亡(Necroptosis)、细胞焦亡(Pyroptosis)、铁死亡(Ferroptosis)、PARP1依赖的死亡(Parthanatos)、内亡或者侵入性细胞死亡(Entotic cell death)、依赖中性粒细胞外诱捕网的网补死亡(Ne...
内质网应激特有caspase-12凋亡途径在高糖刺激的条件永生型小鼠足细胞中的作用 role of the ers-associated specific caspase-12-dependent pathway in the apoptosis of differentiated mouse podocytes induced by high glucose.pdf 2015-03-16上传 内质网应激特有caspase-12凋亡途径在高糖刺激的条件永生型小鼠足细胞中的作...
Therefore, the apoptosis-induced mechanisms by ICD-85 are through activation of caspase-8 and concerning the least cytotoxic effect on MRC-5 cells, ICD-85 may be used as anticancer compound to inhibit growth of cancer cells. 展开 关键词: Caspase-8 Apoptosis Extrinsic pathway HeLa cells ...
3) caspase-dependent pathway caspase依赖途径 1. Etoposide-induced apoptosis in RGC-5 via caspase-dependent pathway; Etoposide经由caspase依赖途径诱导RGC-5细胞凋亡4) transcription-independent 转录非依赖凋亡5) Apoptosis pathway 凋亡途径 例句>> ...
Selective inactivation of a FADD-dependent apoptosis and autophagy pathway in immortal epithelial cells Although evasion of apoptosis is thought to be required for the development of cancer, it is unclear which cell death pathways are evaded. We previously id... J Thorburn,F Moore,A Rao,... ...