Apoptosis and Caspase-3, Rate My ScienceMolecular cloning of the interleukin-1 beta converting enzymeCaspasa
Cell death, caspase 3 activity and enhanced expression of p53, c-Jun , and ATF3 was attenuated in neuroblastoma cells that had been treated with the antioxidant N-acetyl cysteine, indicating that arsenic trioxide cytotoxicity is based on the generation of oxidative stress. Experiments involving ...
《Overexpression of hsa_circ_0007534 predicts unfavorable prognosis for osteosarcoma and regulates cell growth and apoptosis by affecting AKT/GSK-3β signaling pathway》 作者:Baoquan Li,Xiaoguang Li 期刊:Biomedicine & Pharmacotherapy 影响因子:3.743 PMID:30142548 ...
Caspase-3 is one of the members of the family of caspases (cysteine-aspartic-proteases) which are proteolyticenzymesknown for their key roles inapoptosisand controlling inflammation (Hu et al., 2020). In all the enzymes or proteins that are known to be implicated in the execution and activatio...
全称 caspase 3, apoptosis-related cysteine peptidase 别名 CASP3, Caspase3, Caspase-3, Caspase 3, CASP-3 计算分子量 32 kDa 观测分子量 32-35 kDa, 17 kDa, 19 kDa GenBank蛋白编号 NM_004346 基因名称 Caspase 3 Gene ID (NCBI) 836 RRID AB_10733244 偶联类型 Unconjugated 形式 Liquid 纯化方式...
large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. Caspase-3 is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteo...
In addition, the specific caspase-3 inhibitor, Ac-DEVD-CHO, decreased the percentage of apoptotic cells. The purified B-subunit of Stx1 did not induce apoptosis in THP-1 cells. Caspase-3 activation, DNA fragmentation and chromatin condensation caused by Stx were completely blocked by ...
产品类型半胱天冬酶 3/7 试剂 数量1.75 mL 检测方法荧光 产品规格滴瓶 Unit SizeEach 内容与储存 1× 1.75 mL 滴瓶 在≤ 25°C 下储存。 图表 CellEvent™ Caspase 3/7 Green ReadyProbes® reagent Capturing apoptosis with CellEvent® Green and the EVOS® FL Auto imaging system ...
CONCLUSION: Apoptosis and caspase-3 are not only involved in the long-term renal I/R injury, but also mediate the divergent effects of immunosuppression in this model. 展开 关键词: apoptosis caspase-3 immunosuppressants ischemia/reperfusion injury ...
Ac-DEVD-CHO是一种非常强的Caspase 3抑制剂,可以抑制由Caspase3激活导致的细胞凋亡。也可以抑制Caspase 7。Ac-DEVD-CHO是一种可逆的Caspase 3抑制剂,也是最常用的细胞凋亡抑制剂之一,常用于观察特定的细胞凋亡是否通过Caspase 3激活来介导。可以用于抑制培养细胞内的Caspase 3,也可用于抑制体外纯化或粗抽提的Caspase...