Caspase-3 activity in cancer cells was analyzed using Caspase-3/CPP32 Colorimetric Assay Kit.Sujatha RamasamyNorhanom Abdul WahabNurhayati Zainal AbidinSugumaran ManickamZubaidah Zakaria
Caspase-3 activity was detected by applying a caspase-3/CPP32 Colorimetric Assay Kit. Results: In these MSCs, aspirin induced morphological changes ... L Deng,S Hu,AR Baydoun,... - 《Cell Prolif》 被引量: 99发表: 2010年 Characterization and immunostimulating effects on murine peritoneal macr...
海南医学院李孟森团队发表了甲胎蛋白(AFP)抑制caspase-3活性精准位点的重要研究成果。 2017年8月7日,国际著名肿瘤杂志《International Journal of Cancer》(2016-IF: 6.513)以题为“Structural basis for alpha fetoprotein-mediated inhibition of caspase-3 activity in hepatocellular carcinoma cells”发表海南医学院李孟...
结论胃癌原发灶癌细胞中caspase-3表达下调和浸润淋巴细胞中caspase-3表达上调与胃癌发生有关,由caspase-3介导的细胞凋亡与胃癌的发生与发展有关关键字:胃癌caspase-3病理学凋亡【Abstract】Purpose:Tostudytheroleofcaspase-3expressionandapoptosisincarcinogenesisandprogressionofgastriccancer.Methods:Epithdialcellsofmucosa...
Paradoxically, overexpressionof procaspase-3 (PC-3), the low-activity zymogen precursor to caspase-3,has been reported in a variety of cancer types. Until recently, thiscounterintuitive overexpression of a pro-apoptotic protein in cancerhas been puzzling. Recent studies suggest subapoptotic caspase-...
Conclusion The difference in expression of Livin between adenoma and adenocarcinoma indicates the potential value of it in carcinogenesis of colorectal cancer, which suggestes that suppressing Caspase-3 protein activity is one of the channels by which livin promotes colorectal carcinogenesis. 引用本文: ...
摘要:Provided are methods of selecting a treatment for a cancer in a subject in need thereof, by analyzing activity of Yes associated protein 1 (YAP) in cancer cells of the subject, and methods of treating cancer using a therapeutically effective amount of an caspase-3 inhibitor. Also ...
Expressions of survivin and caspase-3 in human non-small cell lung cancer and their relationship with cell apoptosis Background and objective Survivin, a member of inhibitor of apoptosis protein (IAP) family, can directly inhibit caspase-3 and caspase-7 activity and plays... J Wang,L Chen,W...
[4]Bcl-2 overexpression attenuates resveratrol-induced apoptosis in U937 cells by inhibition of caspase-3 activity.Park JW,Choi YJ,Suh SI,et al.Carcinogenesis.2001 [5]Food-derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome C release and apoptosis.Mouria M,Gukovskaya ...
dependently after APG treatment (Figure 1E–G). In Western blot analyses, time course experiments indicated that APG increased caspase-3 and caspase-9 cleavage in AGS and SNU-638cells(Figure 1H).This finding suggests that APG exerts an anti-cancer effect via apoptosis and cell death in GC ...