This chapter reviews the characteristics of the cardiac action potential (AP), with emphasis on major currents responsible for the various components or phases of the APs, as well as the regional differences in cardiac APs. Some cardiac cells display automaticity, because of the presence of a ...
Joseph Feher, in Quantitative Human Physiology (Second Edition), 2012 Summary The cardiac action potential takes a different form in different cardiac cells, which include SA nodal cells, atrial muscle cells, AV nodal cells, Purkinje fibers, and ventricular muscle cells. We consider here the actio...
Cardiac Action Potentials CardiacActionPotentials Reading:•Klabunde,CardiovascularPhysiologyConcepts –Chapter2(ElectricalActivityoftheHeart)pages18-26 TheCardiacActionPotentialTypesAreEitherFastOrSlowResponse •Fast-responseactionpotentials –Atrialmyocardialfibers–Ventricularmyocardialfibers–Purkinjefibers •Slow-...
Action potential phases: Phase 0: Rapid depolarization-↑ Na+ and ↓ K+ conductance Phase 1: Initial repolarization -↓ Na+ and ↑ K+ conductance Phase 2: Plateau phase-↑ Ca++ conductance Phase 3: Repolarization-↑ K+ and ↓ Ca++ conductance Phase 4: Resting potential - ↑ K+ and ↓...
Automated analysis of action potentials from cardiac Purkinje fibers was implemented using a microcomputer system. A dual sampling rate was used during ana... V Elharrar,DE Lovelace - 《American Journal of Physiology》 被引量: 24发表: 1979年 Voltage- and Rate-Dependent Depression of Vmax of Ac...
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The article presents information on cardiac muscle physiology. It describes the work cells and pacemaker cells of the cardiac myocyte. It discusses the distinction of the cardiac action potential from what can be seen in nerves. It relates the role of calcium in the excitation contraction coupling...
(AV) bundle of His, bundle branches, and Purkinje fibers. The action potential for the conductive cells consists of a prepotential phase with a slow influx of Na+followed by a rapid influx of Ca2+and outflux of K+. Contractile cells have an action potential with an extended plateau phase...
Noradrenaline biphasically affects the duration of the action potential (AP) of guinea-pig cardiac ventricular muscle. Low concentrations (10–7 M) prolong the AP duration, while high (10–5 M) concentrations shorten it after an initial prolongation. The extent of the AP-prolonging effect is mo...