Esophageal squamous cell carcinoma is a major histological type of esophageal cancer, with distinct incidence and survival patterns among races. Although previous studies have characterized somatic mutations in this disease, a rigorous comparison between different patient populations has not been conducted. ...
Ductal carcinomais a common type ofbreast cancerthat starts in cells that line the milk ducts, which carry breast milk to the nipple. There are two types: Invasive ductal carcinoma (IDC) Ductal carcinoma in situ (DCIS), also called intraductalcarcinoma ...
Fumarate hydratase (FH) deficient renal cell carcinoma (RCC) is a type of tumor with definite metabolic disorder, but the mechanism of metabolic remodeling is still unclear. LncRNA was reported to closely correlate with cancer metabolism, however the biological role of LncRNA in the development of...
Tumor development, progression, and prognosis remain at the front position of medical research. Two hypotheses of the origin of cancer have existed for many decades. One hypothesis postulates that adult stem or precursor cell is the cell of origin for cancer, whereas the other declares a somatic ...
The preoperative differentiation between RCC and TCC is important in order to identify the type of surgical treatment required: Nephrectomy or ureteronephrectomy. The role of ureteroscopy and biopsy is emphasized in the accurate preoperative diagnosis of a renal pelvic mass. Thus, the present study ...
There are only a few studies involving the Indian population, which has a high incidence of gallbladder cancer. Indians are ethnically and culturally different from their Western counterparts, for whom the incidence of this disease is comparatively low. The present study was conducted prospectively ...
High-grade serous ovarian carcinoma (HGSOC) is the most aggressive type of ovarian cancer, often diagnosed at advanced stages. Molecularly, HGSOC shows high degree of genomic instability associated with large number of genetic alterations. BRD4 is the 4t
The results indicate that AXL is highly expressed in PTC tissue (yellow arrow) Full size image Correlation of AXL expression in PTC tissues with clinicopathological characteristics AXL immunohistochemistry results from patient PTC tissues were compared to the patient clinicopathological data. The Kruskal...
Gastric neuroendocrine carcinoma (GNEC) is a common type of neuroendocrine carcinoma (NEC) with a poor prognosis and limited therapeutic options. The underlying mechanisms of chemoresistance in patients with GNEC and those with NEC are largely unknown, and thus, reliable biomarkers and therapeutic targe...
Nasopharyngeal carcinoma (NPC) is a unique type of head and neck carcinoma, which is common in Southeast Asia and southern China, where it brings significant economic pressure and health burden1. In routine clinical therapy, radiotherapy is the most commonly used method, followed by chemotherapy. ...