CAR T cell therapy for solid tumors: bright future or dark reality? Mol. Ther. 28, 2320–2339 (2020). CAS PubMed PubMed Central Google Scholar Tantalo, D. G. et al. Understanding T cell phenotype for the design of effective chimeric antigen receptor T cell therapies. J. Immunother. ...
[1]https://endpts.com/exclusive-carl-junes-tmunity-encounters-a-lethal-roadblock-as-2-patient-deaths-derail-lead-trial-raise-red-flag-forcing-a-rethink-of-car-t-for-solid-tumors/ [2]https://mp.weixin.qq.com/s/1AaFqrbse6G-TqmyqP8Zqg [3] CAR T-cell therapy for solid tumors. Lancet...
[1]https://endpts.com/exclusive-carl-junes-tmunity-encounters-a-lethal-roadblock-as-2-patient-deaths-derail-lead-trial-raise-red-flag-forcing-a-rethink-of-car-t-for-solid-tumors/ [2]https://mp.weixin.qq.com/s/1AaFqr...
2023年2月22日,中山大学曹庆东、黄曦及霍雯雯共同通讯在Advanced Materials在线发表题为“Genetically Programmable Vesicles for Enhancing CAR-T Therapy against Solid Tumors”的研究论文,该研究表达高亲和力抗PD-L1 单链抗体(抗PD-L1 scF...
1# Rogelio A. Hernandez-Lopez et al. T cell circuits that sense antigen density with an ultrasensitive threshold. Science. (2021)2# A leap forward in research on CAR T cell therapy（来源：Medical press）3# Cellular Engineering Boosts CAR-T Therapy against Solid Tumors（来源：Genetic Engineering...
Modular chimeric cytokine receptors improve CAR T–cell therapy for solid tumorsstjude.org/media-resour 免责声明:本文仅作信息交流,文中的观点不代表中肽生化立场,亦不代表中肽生化支持或反对文中观点。本文也不构成投资建议,也不是研究治疗方案推荐。如果需要获得治疗方案指导,请前往正规医院就诊。
There is an explosion of preclinical and clinical efforts to expand the therapeutic indications for CAR T cell therapies, with a specific focus on improving their clinical utility, particularly for the treatment of solid tumors. In this chapter, we will highlight the recent progress, challenges, ...
CAR-T cell therapies are currently only approved for blood cancers, but new preclinical research shows promise in using CAR-T cells against solid tumors in gastric cancer. CAR-T Cell Therapy for Solid Tumors? CAR-T cell therapy is already a promising cancer treatment strategy, with FDA ...
genome engineering to create new forms of engineered cells with enhanced functionalities. The emergence of synthetic biology approaches for cellular engineering provides a broadly expanded set of tools for programming immune cells for enhanced function. Barriers to therapy of solid tumors will be ...
1.T Cell-Engaging Therapy for Solid Tumors. Clin Cancer Res. 2020 Oct20: clincanres. 2448. 2020. 2. Next generation chimeric antigen receptor T cells: safetystrategies to overcome toxicity. Mol Cancer. 2019 Aug 20;18(1):125. 更多生物制药知识尽在微信公众号"小药说药", 欢迎大家关注阅览!