相关研究结果发表在2019年9月的Nature Medicine期刊上,论文标题为“Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR”。在这项称为CARPALL的临床试验中,他们在患有复发性ALL的儿童和青年人中测试了这种新型的CAR-T细胞疗法。 图片来自N...
Cell expansion is typically a long and labor-intensive step in CAR-T cell manufacture. The Xuri Cell Expansion System (CES) W25 semiautomates this step while functionally closing the process. Cells for autologous or allogeneic cell therapies are cultured inside a single-use Xuri Cellbag ...
CAR-T 疗法就是嵌合抗原受体T细胞免疫疗法，英文全称 Chimeric Antigen Receptor T-Cell Immunotherapy。这是一种治疗肿瘤的新型精准靶向疗法，近几年通过优化改良在临床肿瘤治疗上取得很好的效果，是一种非常有前景的，能够精准、快速、高效，且有可能治愈癌症的新型肿瘤免疫治疗方法。T 细胞也叫 T 淋巴细胞，是人体白...
我们期待这一技术能尽快在临床上得到应用,为患者带来更快更好的治疗。 参考资料: [1] Scaffolds that mimic antigen-presentingcellsenable ex vivo expansion of primary T cells [2] Fast-tracking T cell therapies with immune-mimicking biomaterials
A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity. Chimeric antigen receptor (CAR) T cell therapy is routinely used to treat patients with refractory hematologic malignan...
2、Kim M Y, Jayasinghe R, Devenport J M, et al. A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity[J]. Nature communications, 2022, 13(1): 1-17.3、Heard A, Landmann J H, Hansen A R, et al. Antigen glycosylation ...
原文:Optimization of therapeutic T cell expansion in G-Rex device and applicability to large-scale production for clinical use .Cytotherapy 24 (2022) 334-343 北京泽平科技g-rex细胞培养系统技术代理,请搜索“北京泽平科技”获取原文及其他技术信息。
Ghorashian, Sara et al. Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR.Nature medicinevol. 25,9 (2019): 1408-1414. doi:10.1038/s41591-019-0549-5 Park, Spencer et al. Mi...
1#Immunity boosting treatment enhances CAR-T cell therapy for blood cancers (来源:Medical press) 2#Miriam Y. Kimet al. A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity. Nature Communications. (2022) ...
1#Immunity boosting treatment enhances CAR-T cell therapy for blood cancers (来源:Medical press) 2#Miriam Y. Kimet al. A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity. Nature Communications. (2022) ...