Launching the strategy, the health secretary for England, Andrew Lansley, said, "Our ambition is simple, to deliver survival rates among the best in Europe, and this strategy outlines how we will make our first steps towards this." He said the aim is to reduce the number of deaths from ...
Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer. Sci. Transl. Med. 9, eaal4922 (2017). Article PubMed PubMed Central Google Scholar Sun, S. et al. Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2...
5) adaptability in the sense that any CAS can vary its strategy and tactics according to a new or previously experienced situation. The listed hallmarks of autonomously functioning systems are unimaginable without synergy, which implies an orchestrated, synchronized and interdependent behavior of all...
The Accelerated Access Collaborative – a body established by the government as part of the Life Sciences Industrial Strategy to speed up the adoption and uptake of innovative new treatments – will meet next week to discuss how it can support implementation. Stevens said at the Confed19 conference...
Patients in the UK faced long waits for treatment, and this varied depending on where they lived. The average time to start chemotherapy was shortest in England (48 days) and longest in Scotland (65 days). Northern Ireland had the shortest average time to start radiotherapy (53 days) and ...
Regulation of p53 stability as a therapeutic strategy for cancer. Biochemical Pharmacol. 2021;185:114407. Article CAS Google Scholar Wang F, Gómez-Sintes R, Boya P. Lysosomal membrane permeabilization and cell death. Traffic. 2018;19:918–31. Article CAS PubMed Google Scholar Johansson AC, ...
Cancer Biology, Chemo-resistance reversal Strategy, Drug Combination, Cell Line Developer Alessandro Rizzo, MD Giovanni Paolo II Cancer Institute IRCCS, Bari, Italy Renal cell carcinoma, Cholangiocarcinoma, Gastric cancer, Immunotherapy, Biliary tract cancer, Hepatocellular carcinoma, Breast cancer, Urothelia...
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(ACTs), along with their regulatory approvals. In recent times, there has been hope in the effectiveness of cancer vaccines for therapy as they have been able to stimulate de novo T-cell reactions against tumor antigens. These tumor antigens include both tumor-associated antigen (TAA) and ...
Cancer Reform Strategy. 2007. https://www.nhs.uk/NHSEngland/NSF/Documents/Cancer%20Reform%20Strategy.pdf. Department of Health. The NHS Long Term Plan. 2019. https://www.longtermplan.nhs.uk/publication/nhs-long-term-plan/. Department of Health, Cancer Research UK. The National Awareness ...