Cancer stem cells are rare immortal cells within a tumour that can both self-renew by dividing and give rise to many cell types that constitute the tumour, and can therefore form tumours. Such cells have been found in various types of human tumours and might be attractive targets for cancer...
Targeting glioma stem cells through combined BMI1 and EZH2 inhibition Microenvironmental pressures in glioblastoma select for glioma stem cells (GSCs) subpopulations that are maintained through preferential activation of BMI1 and EZH2 in different niches. Given the high degree of intratumor heterogeneity, ...
Stem cellsMesenchymal stem cells (MSC) have been explored as a new clinically relevant cell type to repair injured tissue. A growing corpus of studies have highlighted two important aspects of MSC therapy: (1) MSCs can modulate T-cell mediated immunological responses, and (2) systemically ...
Cancer Stem Cells Isolate, Verify, and Investigate ISOLATE VERIFY INVESTIGATE The CSC Hypothesis Like all stem cells, oncogenically transformed cancer stem cells Unlike the differentiated cancer cells in a tumor, xeno- (CSCs) are defined by their ability for self-renewal and multi potency. ...
Webinar: ALDEFLUOR™ and Cancer Stem Cells This webinar video explains the principles of ALDEFLUOR™ technology, offers literature review and summary of technical considerations of performing and interpreting ALDEFLUOR™ assays on primary tissues and tumor cell lines. To view the webinar, please...
Cancer Stem Cells (肿瘤干细胞)抑制剂 MCE 国际站:Cancer Stem Cells 品牌:MedChemExpress (MCE) 概述:癌症干细胞(CSC)是具有干细胞特性的癌细胞群,即自我更新和产生分化后代的能力。 CSC 具有高可塑性,可改变其表型和功能外观。它们在肿瘤的发生、扩展、耐药、复发和转移中发挥着重要作用。多项研究表明,CSC ...
Cancer Stem Cell News is an online resource that curates the top research publications and reviews about cancer progenitor cells and cancer stem cells.
Since their initial identification three decades ago, there has been extensive research regarding cancer stem cells (CSCs). It is important to consider the biology of cancer stem cells with a particular focus on their phenotypic and metabolic plasticity, the most important signaling pathways, and non...
Join us at the16th International Conference on Cancer Stem Cell & Oncology Research (Cancer Stem Cells 2025), taking place onApril 21-22, 2025, in the vibrant city ofAmsterdam, Netherlands. This conference will focus on the theme "Precision Medicine Approaches for Cancer Stem Cell Targeting," ...
Importantly, minimal residual diseases are highly enriched for cancer stem cells (Ghiaur et al., 2012). The cancer stem cell (CSC) concept was first reported more than a century ago on observing the histological similarities between tumors and embryonic tissues. A tumor contains heterogeneous ...