Cancer of the blood plasma cells
This is a cancer of the plasma cells in bone marrow. Plasma cells are a type of white blood cell that makes antibodies. Myeloma cells spread through the bone marrow. They can damage your bones and crowd out healthy blood cells. These cells also make antibodies that can't fight off infecti...
单位:复旦大学附属中山医院检验科 2024年1月18日,复旦中山检验科最新研究成果《Detection of Circulating Plasma Cells in Peripheral Blood Using Deep Learning-Based Morphological Analysis》在国际权威杂志Cancer(IF=6.2,JCR Q1区,Doi:10.100...
In parallel with efforts to identify tumor-based biomarkers, an enormous effort has been made recently to develop blood-based biomarkers to predict patient response to ICI. Investigation of the status and activity of the systemic immune system is non-invasive, allows for relatively easy and dynamic...
Among non-epithelial cells, PYCR1 was expressed in plasma cells and CAFs, particularly in a subset of myCAFs that express higher levels of COL1A1 (Fig. 2f,g and Extended Data Fig. 2a,b). In contrast, PYCR2 was expressed by few CAFs (Extended Data Fig. 2c), in line with our in ...
Liquid biopsies provide a means for the profiling of cell-free RNAs secreted by cells throughout the body. Although well-annotated coding and non-coding transcripts in blood are readily detectable and can serve as biomarkers of disease, the overall diagnostic utility of the cell-free transcriptome...
WASHINGTON, Feb. 25 (Xinhua) -- Researchers at the University of Kansas invented a sensitive device that may detect cancer and other diseases quickly from a droplet of blood. The study published on Monday in the journal Nature Biomedical Engineering reported the "lab-on-a-chip" device that co...
In MGUS (monoclonal gammopathy of undetermined significance), the blood's plasma cells produce an abnormal protein called monoclonal protein that may cause multiple myeloma, a blood cancer that can crowd out the bone marrow's normal blood-forming cells. ...
Regulatory T (Treg) cells play a major role in the development of an immunosuppressive tumor microenvironment. The origin of intratumoral Treg cells and their relationship with peripheral blood Treg cells remain unclear. Treg cells consist of at least three functionally distinct subpopulations. Here we...
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