A rare case of bladder cancer that metastasized to brain, heart, and lung lymph nodes benefited from immunotherapyBladder cancerBrain metastasisHeart metastasisImmunotherapyTislelizumabBladder cancer is a common malignant tumor of the genitourinary system, with the primary cause of death being metastasis...
A case of breast cancer metastasized to the brain 28 years after mastectomy in a 74-year-old woman is reported. The patient had undergone a mastectomy because of right breast cancer at the age of 46. Histopathological diagnosis of the tumor was invasive ductal carcinoma papillo-tubular type, ...
When grown as mammary tumours, CN34-BrM2 metastasizedto brain in 42% (5 out of 12) of the mice, whereas parental CN34mammary tumours yielded no brain metastases in ten mice. BrM2cellsshowednoincreaseinboneorlungmetastaticactivitycomparedto the parental populations (Supplementary Table 1). MDA...
The invention relates to methods for determining whether a melanoma will metastasize or has metastasized to the small intestine in a subject by detecting or quantifying the expression of the CCR9, CCL25/TECK, or integrin α4 gene. Also d... Dave S.B. Hoon,F Amersi 被引量: 0发表: 2009...
SKBR3 is also a useful preclinical model system to screen for the effectiveness of therapeutic agents that target HER2 cancers and to investigate resistance mechanisms that evolve in response to HER2-targeted therapies21. Last, in contrast to other brain metastasized breast cancers, the SKBR3 cells...
The researchers' next step is to initiate a collaboration with CAR T-cell experts to further understand how CAR T-cell therapy can be targeted to IL13Ra2. Eventually, Cittelly hopes to see clinical trials for patients withbreast cancerthat has metastasized to the brain, as they are currently...
brain metastases, their survival time was shorter than those with hormone receptor–positive or HER2-positive breast cancer who experienced brain metastases. Higher risks of brain metastases were also seen in patients whose cancer had metastasized to other parts of the body besides the brain, ...
"Unfortunately, mine metastasized to my brain so I will continue to be in active treatment for the rest of my life. Since the initial diagnosis is my cancer had spread to my brain, and I've had three brain surgeries." "Unfortunately, her cancer and my cancer were very different," Doan...
metastasized to the brain71. More importantly, by transferring lncRNA GS1- 600G8.5, the exosomes from the high brain mBC cells could be internalized by brain microvascular endothelial cells, which disrupted the permeability of the blood–brain barrier (BBB) and promoted the passage of cancer ...
all 18-year-old women, were found to have developed brain tumors. Cranial scans were performed only after the patients developed symptoms including severe headaches and changes in mental status. The tumors had also metastasized to the lungs of the three patients, one of whom had died when the...