2018年12月12日,中国人民解放军第 86 医院朱志远(音译,Zhu Zhi-Yuan)等人在Cancer Biotherapy and Radiopharmaceuticals在线发表题为“Silencing of MEOX1 Gene Inhibits Proliferation and Promotes Apoptosis of LNCaP Cells in Prostate Cancer”的研究论文,该研究发现MEOX1基因沉默可降低LNCaP细胞的增殖和凋亡,有望成为...
"Radiotherapy and, potentially, Low Temperature Plasma are really effective ways to kill cancer cells. The problem always is that a proportion of the cancers relapse. By unpicking the responses of cells from men with prostate cancer in Yorkshire we have unearthed a solution. "The implication is ...
今天和大家分享一篇2021年8月1日online的利用生物力学技术研究循环肿瘤细胞力学性质的文献,题目“Contacts with Macrophages Promote an Aggressive Nanomechanical Phenotype of Circulating Tumor Cells in Prostate Cancer”,本文发表于美国癌症研究协会(AACR)期刊《CancerResearch》。 我们知道,实体肿瘤(Solid tumor)会通过其...
Neuroendocrine cells are the third type of prostatic epithelial cells in addition to secretory cells and basal cells in normal prostate glands. Neuroendocrine cells in prostate cancer are believed to derive from neuroendocrine cells or their stem precursors....
Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might
Prostate cancer cells have robust telomerase activity and several commonly used prostate cancer cell lines show a significant TRAP signal (Fig. 1A). Similar to the results observed in primary tumor samples (data not shown), these cell lines have relatively short telomeres (Fig. 1B). The cell ...
Further, in prostate cancer cells Orai3 was shown to form hetero-multimeric channels with Orai1 [75]. These Orai1/Orai3 hetero-multimeric channels mediate store-independent Ca2+ influx and enhance apoptotic resistance of prostate cancer cells [75,76]. A similar apoptotic resistance role for Ora...
前列腺癌细胞,该细胞能产生逆转录病毒需要在生物安全等级2级的实验室环境中操作细胞。22RV1细胞表达前列腺特异抗原PSA。二羟基睾丸脂酮可轻微刺激细胞生长,经western blot检测溶解产物与雄激素受体抗体起免疫反应。EGF可刺激细胞生长,但TGF-β1不能抑制细胞生长。近期证实22RV1可生产高滴度的人逆转录病毒XMRV。在裸鼠...
Neuroendocrine (NE) cells are found in prostate tumors, and their incidence is considered a promising prognostic indicator for the development of androgen-independent disease. NE cells are derived from non-NE prostate cancer cells and secrete factors that can act in a paracrine manner to stimulate ...
JunD, a member of the AP-1 family, is essential for cell proliferation in prostate cancer (PCa) cells. We recently demonstrated that JunD knock-down (KD) in PCa cells results in cell cycle arrest in G1-phase concomitant with a decrease in cyclin D1, Ki67, and c-MYC, but an increase...