HER2: Human epidermal growth factor receptor 2 APRI: Aspartate transaminase–to-platelet ratio index ML: Machine learning CNN: Convolutional-neural-network RNN: Recurrent-neural-network DCNN: Deep convolutional neural network LSTM: Long short-term memory DCNN-US: Deep convolutional neural net...
aPositive results for drug combo in I-SPY 2 trial. 正面结果为药物组合在I-SPY 2试验。 [translate] aHeight, body mass index (BMI), BMI change, and the risk of estrogen receptor-positive, HER2-positive, and triple-negative breast cancer among women ages 20 to 44 years. 高度、身体许多索引...
Hormone receptor-positive, HER2 negative, and node-negative breast cancer with low tumor stage, indicate a favorable prognosis [5]. Breast cancer primarily spreads via the lymphatic system (locally), and less frequently through the bloodstream [6]. If distant metastases occur, the predominant sites...
Using a computational technique, the team grouped together cancer cells in which similar sets of genes were turned on or off and found there were actually 10 categories of breast cancer cells. Just three categories of breast cancer cells (hormone-positive, HER2-positive, and triple-negative) are...
In patients with HER2-positive or triple-negative metastatic breast cancer, the average symptom severity scores were significantly lower than those observed in patients with estrogen receptor/progesterone receptor-positive or HER2-negative metastatic breast cancer (p=0.033). Patients in the fourth-line ...
Consequently, a key question is how the relatively small absolute benefit of chemo- therapy in node-negative, ER-positive, tamoxifen-treated women weighs against the harm of adverse drug effects, par- ticularly when as many as 85% of such women who do not receive chemotherapy may remain ...
Estrogen Receptor (ER): Positive Tumor cells with nuclear positivity: 95% Average intensity of staining: 3+ Progesterone Receptor (PR): Negative Tumor cells with nuclear positivity: <1% Average intensity of staining: 1+ Her2 by IHC: Equivocal ...
many international cohorts of cancer patients have shown negative prognostic value for TAMs expressing CD68, CD163, CD204, CD206, MARCO, and stabilin-1 [9,28]. In several in vitro and in vivo studies, both the pro- and antitumor activities of SRs have been demonstrated to be dependent on...
Long-Term Survival of Advanced Breast Cancer with Letrozole and Palbociclib: Can the Intent Change from Palliation to Cure?Advanced breast cancerLetrozole and palbociclibLong-term survivalWe report a patient with advanced hormone-positive, HER2-negative breast cancer with contralateral supraclavicular node...
many international cohorts of cancer patients have shown negative prognostic value for TAMs expressing CD68, CD163, CD204, CD206, MARCO, and stabilin-1 [9,28]. In several in vitro and in vivo studies, both the pro- and antitumor activities of SRs have been demonstrated to be dependent on...