Calcium binding proteins have remarkable sequence homologyand structural similarity, yet they function in a wide range of biologicalprocesses. Several important disease states; hypertension, heart disease, diabetes,manic depression, Alzheimer's disease may result from abnormal remodeling ofcalcium binding ...
This international symposium on calcium-binding proteins and calcium function in health and disease was held at the Univ. of Wisconsin, USA on 8-12 June 1980. One paper presented appears elsewhere in DSA and may be found via the subject ... PV Hauschka - 《Calcium Binding Protein & Calcium...
This review article discusses the current knowledge on the structure and potential function of this protein. Several putative binding partners of ALG-2 have been identified hinting to functions of ALG-2 in apoptosis and possibly also in proliferation, endocytosis and transcriptional regulation during ...
Intracellular neuronal calcium sensor proteins: a family of EF-hand calcium-binding proteins in search of a function. Cell Tissue Res 1999; 295: 1–12. 104 Lautermilch NJ, Few AP, Scheuer T, Catterall WA. Modulation of CaV2.1 channels by the neuronal calcium-binding protein visinin-like ...
Calcium-Binding Proteins Calcium exerts its control in cellular function by virtue of its ability to regulate the activity of many different proteins, such as channels, transporters, and transcription factors. In the majority of cases, a calcium-binding protein serves as an intermediate between ...
The calcium ion (Ca2+) is a ubiquitous and essential secondary messenger in all eukaryotic organisms and plays an important role in all aspects of cell function, including mediating responses to various biotic and abiotic environmental cues11,12. Calcium-binding proteins, which are a component of ...
Furthermore, mutations that affect the interaction between BON1 and its functional partner BAP1 abolished BON1 function. This analysis reveals an unanticipated regulation of copine protein localization and function by calcium and lipid modification and suggests an important role in protein-protein ...
Distinct subpopulations of neurons in the brain contain one or more of the Ca2+-binding proteins calbindin D28k, calretinin, and parvalbumin. Although it h... PS Chard,J Jordan,CJ Marcuccilli,... - 《Proc Natl Acad Sci U S A》 被引量: 296发表: 1995年 Design and function of superfast...
The present invention relates to regulation of cardiac contractile function. The present invention is based on the discovery that administration or overexpression of the protein sorcin enhances cardiac contractile function. Accordingly, the present invention relates to methods of increasing cardiac contractile...
The cloning of a Drosophila homolog to vertebrate neuronal Ca(2+)-binding proteins opens new routes to study the so far largely elusive function of these brain molecules. 展开 关键词: Animals Drosophila Calcium-Binding Proteins DNA Drosophila Proteins In Situ Hybridization Base Sequence Protein ...