今天给各位翻译的是2014年《Nucleic Acids Research》期刊文章:Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance。 摘要 人类端粒酶(hTR)的RNA成分定位于Cajal小体并且已经提出Cajal小体在端粒酶全酶组装和端粒酶运输中发挥作用。在这里,Cajal小体在...
网络卡哈尔体 网络释义 1. 卡哈尔体 但它对酶的活性来说并不是必需的,它只是给称为卡哈尔体(Cajalbodies)的细胞核中的处理和保持区域补充端粒酶复合物。 … www.bioon.com|基于19个网页
端粒酶重新启动需要TCAB1和Cajal小体独立存在 今天给各位翻译的是2012年《Molecular and Cellular Biology》期刊文章:Telomerase Recruitment Requires both TCAB1 and Cajal Bodies Independently。 摘要 大多数癌细胞无限生长的能力依赖于端粒酶及其对端粒的募集。在人类细胞中招募依赖于Cajal小体RNA伴侣TCAB1与端粒酶RNA亚单...
Cajal bodies (CBs) are distinct sub-nuclear structures that are present in eukaryotic living cells and are often associated with the nucleolus. CBs play important roles in RNA metabolism and formation of RNPs involved in transcription, splicing, ribosome biogenesis, and telomere maintenance. Besides ...
Cajal bodies (CBs), until recently known as coiled bodies, are revealed by silver staining as prominent spots in nuclei. Their purpose has been mostly a mystery since their discovery 98 years ago. They look similar to nucleoli, the cell's ribosome factories, and often lie close to them. ...
While Cajal bodies have beendetected in many species, theyare not visible in every cell type ortissue within a given species. Theyare most prominent in cell typessuch as neurons that are activelyengaged in transcription and thusrequire large quantities ofsnRNPs. Another misconceptionis that the ...
Cajal bodies, or CBs, are universal entities found in both the nucleolus and nucleoplasm of most living cells. Their function relates to RNA metabolism, including transcription, splicing, stable RNA modification, small RNA biogenesis, gene silencing, nonsense-mediated decay and telomere maintenance. ...
Cajal bodies (coiled bodies) are nuclear organelles that contain a variety of components required for transcription and processing of RNA. Cajal bodies in ... GT Morgan,O Doyle,C Murphy,... - 《Journal of Structural Biology》 被引量: 251发表: 2000年 Cajal Bodies, Nucleoli, and Speckles in...
Cajal bodies: the first 100 years. Cajal bodies are small nuclear organelles first described nearly 100 years ago by Ramn y Cajal in vertebrate neural tissues. They have since been found in ... JG Gall - 《Annu Rev Cell Dev Biol》 被引量: 781发表: 2003年 Cell cycle–regulated ...
Cajal bodies (CBs) are nuclear organelles that are usually identified by the marker protein p80-coilin. Because no orthologue of coilin is known in Drosophila melanogaster, we identified D. melanogaster CBs using probes for other components that are relatively diagnostic for CBs in vertebrate cells....