Cajal bodies articles from across Nature Portfolio Atom RSS Feed Cajal bodies are regions within the nucleus that are enriched in proteins and RNAs involved in mRNA processing. They are the main sites for the assembly of small nuclear ribonucleoproteins (snRNPs). Latest Research and Reviews ...
This review will focus on Cajal bodies (CBs) and the viruses that target them. Since CBs are dynamic structures, other NBs (principally nucleoli and promyelocytic leukaemia, PML and bodies), whose components interact with CBs, will also be considered. As well as providing important insights into...
The review provides modern classification of evolutionarily conserved coilin-containing nuclear bodies of somatic and germ cells that is based on the characteristic features of their molecular composition and the nature of their functions. The main differences between Cajal bodies and histone locus bodies,...
Its GU-rich sequence in the 5′-region is important for stability and localization to Cajal bodies, while the two subsequent C/D domains are involved in the modification of snRNA (Fig. 1a and Supplementary Fig. 1a)24,27,47. A shorter isoform of scaRNA2 predicted to obstruct a snoRNA ...
Cajal bodies 来自 Semantic Scholar 喜欢 0 阅读量: 101 作者: AG Matera 摘要: Curr Biol. 2003 Jul 1;13(13):R503. Review 关键词:myeloma bisphosphonates apoptosis MAPK S-phase cell cycle arrest DOI: 10.1016/S0960-9822(03)00438-X 被引量: 37 ...
Cajal bodies (CBs) are nuclear organelles that are usually identified by the marker protein p80-coilin. Because no orthologue of coilin is known in Drosophila melanogaster, we identified D. melanogaster CBs using probes for other components that are relatively diagnostic for CBs in vertebrate cells....
jcb mini-review cajal bodies and coilin-moving towards function Examines the function of Cajal bodies in the neuronal cells. Demonstration of high level of transcriptional activities; Participation in cell division; Ass... SC Ogg,AI Lamond 被引量: 0发表: 2018年 ...
In this brief review, I focus on coilin and Cajal bodies. Coilin is a key scaffolding protein of Cajal bodies that is evolutionarily conserved in metazoans. Cajal bodies are thought to be one of the archetypal nuclear structures involved in the metabolism of several short non-coding nuclear ...
Aside from nucleoli, Cajal bodies (CBs) are the best-characterized organelles of mammalian cell nuclei. Like nucleoli, CBs concentrate ribonucleoproteins (RNPs), in particular, spliceosomal small nuclear RNPs (snRNPs) and small nucleolar RNPs (snoRNPs). In one of the best-defined functions of CBs...
The RNA component of human telomerase (hTR) resides in the nucleoplasmic Cajal bodies (CBs) of interphase cancer cells. Here, in situ hybridization demonstrates that in human HeLa and Hep2 S phase cells, besides accumulating in CBs, hTR specifically concentrates at a few telomeres that also ...