Cell lineCharacteristics MDCK (Madin–Darby canine kidney) • Superior model in terms of passive model compared to the Caco-2 model (lower TEER values) • Polarized cells with low intrinsic expression of ABC transporters • A nonhuman (dog) and nonintestinal (renal) cell line • Ideal ...
Caco-2 cells, which are known to spontaneously differentiate in cell culture, adopt typical epithelial characteristics and are widely used as a model to study cellular uptake, transport and metabolism processes. However, groups of flat and undifferentiated cells have been observed amid differentiating ...
The Caco-2 cells spontaneously differentiate to express morphological (polarized columnar epithelium) and functional characteristics of mature small intestinal enterocytes. The polarized Caco-2 cell layer shows 4 times higher TEER values compared to HT29 monolayers, i.e. more similar to the in vivo s...
10.7 Advantages and Disadvantages The Caco-2 cells spontaneously differentiate to express morphological (polarized columnar epithelium) and functional characteristics of mature small intestinal enterocytes. The polarized Caco-2 cell layer shows 4 times higher TEER values compared to HT29 monolayers, i.e....
Transport characteristics of candesartan in human intestinal Caco-2 cell line. Biopharm Drug Dispos 2009;30:259-64.L. Zhou, X. Chen, Y. Gu, J. Liang, Transport characteristics of candesartan in human intestinal Caco-2 cell line, Biopharm. Drug Dispos. 30 (5) (2009) 259-264....
(2002). Permeability characteristics of endocrine-disrupting chemicals using an in vitro cell culture model, Caco-2 cells. Curr. Drug Metab. 3, 551-557.Yoshikawa Y, Hayashi A, Inai M, Matsushita A, Shibata N, Takada K. Permeability characteristics of endocrine-disrupting chemicals using an in...
目的研究牙周致病菌—牙龈卟啉单胞菌(Porphyromonas gingivalis,P.g)对人结肠癌Caco-2细胞增殖和炎症因子表达的影响,及JAK2-STAT3通路是否参与P.g对Caco-2细胞增殖的调控,为进一步探讨P.g与结肠癌之间的关系提供实验依据。方法体外培养Caco-2细胞,选择不同感染复数(multiplicity of infection,MOI)的P.g(0、1、10、...
polymyxa CCM 1465 and 88 A to synthesize silver nanoparticles, and followed by an investigation of the characteristics of the resulting nanoparticles. Show abstract Exploiting the bacterial exopolysaccharide bioconversion using residual cheese whey as culture medium 2025, Preparative Biochemistry and ...
Caco-2 cell line was established from a 72 year old male Caucasian. Upon reaching confluence, the cells express characteristics of enterocytic differenti- ation. Caco-2 cells express retinoic acid binding protein I and retinol binding protein II. REFERENCES 1. Fogh, J., Wright, W.C. and ...
[7] SAMBUY Y,ANGELIS I D,RANALDI G,et al.The Caco-2 cell line as a model of the intestinal barrier:influence of cell and culture related factors on Caco-2 cell functional characteristics[J].Cell Biology and Toxico-logy,2005,21(1):1-26....