Caco-2CellCultureModel APSide(Lumen)BLSide(Serosal)BtoA AtoB ApicaltoBasolateralTransport:AbsorptiveTransportBasolateraltoApicalTransport:SecretoryTransport Effluxtobothsides Caco-2细胞模型的优点①Caco-2细胞虽然是来源于人的结肠癌细胞,但在 很多方面,其功能与人小肠上皮细胞是相似的,同源性好,不会产生上皮...
Caco-2CellCultureModel APSide(Lumen)BLSide(Serosal)BtoA AtoB ApicaltoBasolateralTransport:AbsorptiveTransportBasolateraltoApicalTransport:SecretoryTransport Effluxtobothsides Caco-2细胞模型的优点①Caco-2细胞虽然是来源于人的结肠癌细胞,但在很多方面,其功能与人小肠上皮细胞是相似的,同源性好,不会产生上皮...
16–18)For Caco-2 cell monolayers model, there existed a good correlation between the apparent permeability coefficient and the absorption coefficient of the human body.11,19) Caco-2 细胞单层模型已广泛用于制药行业和学术界的渗透性评估和化合物转运特性的测定。5–7)Caco-2细胞来源于人结肠腺癌细胞,...
LIN Jiali,LIU Yangjie,HAN Fuliang.Establishment of Caco-2 cell model for transporting glucoside compounds[J].Journal of Food Science and Technology,2021,39(4):95-103. 基金项目:国家自然科学基金资助项目(31401479)。
Tested with the Caco-2 model, identical meals induced no difference in ferritin formation (ng/mg cell protein) between varieties alone (ACR 33 ± 4 vs. TZB 37 ± 10; mean ± SD) or with AA (ACR 174 ± 34 vs. TZB 165 ± 37). The absorption ratio in humans (2.6 w/wo AA) was...
形成连续的单层(monolayer)。2021/6/16 6 培育约3星期后,其电阻值达到400Ω(有的要求达到600Ω),它们形成致密的细胞单层,结构和生化作用类似于小肠上皮细胞,3-5天内适合进行转运试验。2021/6/16 7 Caco-2CellCultureModel APSide(Lumen)BLSide(Serosal)BtoA AtoB ...
5、retory TransportB to A Efflux to both sidesCaco-2 Cell Culture ModelCaco-2Caco-2细胞虽然是来源于人的结肠癌细胞,但在细胞虽然是来源于人的结肠癌细胞,但在很多方面,其功能与人小肠上皮细胞是相似的,很多方面,其功能与人小肠上皮细胞是相似的,同同源性好源性好,不会产生上皮细胞形态学和生理学性质...
形成连续的单层(monolayer)。2021/6/16 6 培育约3星期后,其电阻值达到400Ω(有的要求达到600Ω),它们形成致密的细胞单层,结构和生化作用类似于小肠上皮细胞,3-5天内适合进行转运试验。2021/6/16 7 Caco-2CellCultureModel APSide(Lumen)BLSide(Serosal)BtoA AtoB ...
AP Side(Lumen) BL Side(Serosal)Apical to Basolateral Transport: Absorptive TransportA to B Basolateral to Apical Transport: Secretory TransportB to A Efflux to both sidesCaco-2 Cell Culture Model Caco-2细 胞虽然是来源于人 6、 的结肠癌细胞,但 在很 多方面,其功能与人小肠上皮细胞是相似的, ...
[关键词] Caco-2细胞单层模型;跨膜电阻(TEER)值;碱性磷酸酶; [中图分类号] R965 [文献标识码] A [文章编号] 1672-2809(2015)14-0033-04 Establishment of Caco-2 cell monolayer model SUN Xu1,2, LUO Yu-ping2 1 Beijing Key Laboratory, National Center for Safety Evaluation of Drugs, National ...