ArticleCa2+ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effector Author links open overlay panelMingjun Gao 1 11, Yang He 1 11, Xin Yin 1 9 11, Xiangbin Zhong 1 10 11, Bingxiao Yan 1, Yue Wu 1, Jin Chen 1, Xiaoyuan Li 2, Keran Zhai 1, ...
Ca2+ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effectordoi:10.1016/j.cell.2021.09.009Mingjun GaoYang HeXin YinXiangbin ZhongBingxiao YanYue-xuan WuJin ChenXiaoyuan LiKeran ZhaiYifeng HuangCell
The role of mechanosensor Piezo1 in bone homeostasis and mechanobiology. Dev Biol. 2023;493:80–8. Article CAS PubMed Google Scholar Wang Y, et al. Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3...
ROS and ROS-Mediated Cellular Signaling 2016, Oxidative Medicine and Cellular Longevity The clerodane diterpene casearin J induces apoptosis of T-all cells through SERCA inhibition, oxidative stress, and interference with notch1 signaling 2016, Cell Death and Disease Role of calcium signaling in B ...
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Ca2+concentration in the bulges38. The accumulation of ROS also facilitates the softening of the cell wall in the bulges to allow the turgor pressure-driven expansion of the bulge for RH tip growth39,40. Thus ROS and Ca2+form a positive regulatory loop for the RH initiation and tip ...
Fig. 5: Glutamate transporters mediated glutamate-induced ROS production and LCR occurrence. aMeasurement of 5 mM glutamate-induced ROS levels in rat SANPC mitochondria treated with vehicle or 100 μM inhibitors of glutamate receptors/transporters (n = 5–6 per group).bRepresentative confo...
[111]. Consistent with this hypothesis, reduced ATP production in diabetic hearts was observed, presumably due to dysfunctional mitochondria. These findings suggest that mitochondrial Ca2+load acts as a sensor of Ca2+homeostasis in the cell, thereby triggering the pathological outcomes associated with ...
Moreover, multiple Ca2+ channels, such as TRPC3 [129], TRPC6 [123], RyR2 [129,130], ORAI1, as well as the Ca2+ sensor STIM1 [122], participate in the regulation of Ca2+ signaling to controls NF-κB activity (Fig. 5). Show abstract MicroRNA-29a-3p Reduces TNFα-Induced ...
Moreover, a related central question is how differences in Ca2+-signaling that result in specific cellular responses can be mediated by rather similar Ca2+-sensor proteins, which are very often expressed in the same cell type. In order to work on these issues we chose to compare zGCAPs ...