C2H2 Zinc Finger Transcription Factors Associated with HemoglobinopathiesIn humans, specific aberrations in 尾-globin results in sickle cell disease and 尾-thalassemia, symptoms of which can be ameliorated by inc
Comprehensive analysis of the binding specificities of C2H2 zinc finger proteins reveals their DNA recognition code. Cys2-His2 zinc finger (C2H2-ZF) proteins represent the largest class of putative human transcription factors. However, for most C2H2-ZF p
Abe, 2008 Functional analysis of C2H2 zinc finger transcription factor CrzA involved in calcium signaling in Aspergillus nidulans. Curr. Genet. 54: 325- 338.Hagiwara D, Kondo A, Fujioka T, Abe K.2008. Functional analysis of C2H2 zinc finger transcription factor CrzA involved in calcium ...
Genome-wide identification and expression analyses of C2H2 zinc finger transcription factors in Pleurotus ostreatus [J]. PeerJ, 2022, 10: e12654. [20] 吴端, 李文佳, 姚辉, 等. 冬虫夏草菌 C2H2 基因家族鉴 定及其在砷胁迫下表达分析 [J]. 菌物研究 , 2020, 18(2): 110-120. [21] Chen S...
H. Adaptive evolution in zinc finger transcription factors. PLoS Genet. 5, e1000325 (2009). 32. John, S. et al. Chromatin accessibility pre-determines glucocorticoid receptor binding patterns. Nat. Genet. 43, 264–268 (2011). 33. Grontved, L. et al. C/EBP maintains chromatin accessibility...
The present discovery would be helpful for deeper understanding of the regulatory mechanism of a gene with tandem repetitive domains and should have potential to understand and cure diseases caused by abnormality in such transcription factors as C2H2-ZNF proteins....
Abbreviations JA: jasmonic acid; TF: transcription factors; ERF: ethylene-responsive element- binding factor; EAR: ERF-associated amphiphilic repression; NLS: nuclear locali- zation signal; chr: chromosome; SRA: sequence read archive; ZF: zinc finger. Authors' contributions NN: performed all ...
The zinc finger protein, one of the common transcription factors widely exist in eukaryotes, is involved in cell differentiation, proliferation, apoptosis, and other important life processes. Study has indicated that some zinc finger proteins can regulate the stress resistance of plants (Ciftci-Yilmaz...
c2h2 型锌指对生物大分子的识别c2h2 zinc-finger - 药学学报.pdf,834 药学学报 Acta Pharmaceutica Sinica 20 13, 48 (6): 834 84 1 C2H2 型锌指对生物大分子的识别 多* ( 中国医学科学院、北京协和医学院药物研究所, 天然药物活性物质与功能国家重点实验室, 北京 100050)
memberoftranscription factorswhichexists widely in prokaryote andcukaryote.ZincfingerproteinsPLaY all important rolein growth and development inbothanimalsand plants.Thebiggestsubfamily ofzincfingerproteins isC2H2 (Cys2/His2)type zinc fingerprotein,which functionsasa part ofDNA-binding and protein-protein ...