Boiadjiev SE, Lightner DA. Chiroptical properties of compounds con- taining C=O groups. In: Patai S, Rappaport Z, editors. The chemistry of functional groups. Supplement A3: the chemistry of double-bonded functional groups. John Wiley & Sons; 1997. p 224....
The proximity of palmitoyl-CoA to C23 in PHF2 was modeled by enforcing a distance restraint between the sulfur atom (SC23) of C23 and the acyl carbon (Cac; carbon double bonded to oxygen in the acyl group of palmitoyl-CoA). The optimal SC23-Cac distance to be used as the restraint ...
Interestingly, Yu group designed a U-shaped template that led to various types of meta-C–H functionalizations34. In 2013, Yu and co-workers reported the first example of meta-C–H arylation of phenylpropanoic acid and phenol derivatives enabled by a U-shaped covalently bonded template (Fig....
Supplement A3 The chemistry of double-bonded functional groups The series 'The Chemistry of Functional Groups' is planned to cover in each volume all aspects of the chemistry of one of the important functional c groups in organic chemistry. The emphasis is laid on the functional group treated an...
(retinopathy, nephropathy, and neuropathy) was thought to be due to the presence of enriched protective factors against microvascular complications. In two double-blind, placebo-controlled studies in type 1DM patients, C-peptide replacement or placebo was given with the patients’ regular insulin ...
In the cation the manganese–platinum bond [2.628(1)Å] is bridged by the CC6H4Me-4 group [C–Pt 1.968(8), C–Mn 1.829(8)Å] forming a dimetallacyclopropene ring, the C–Mn separation being indicative of a double bond. The 1H, 31P, and 13C (1H decoupled) n.m.r. spe...
In contrast, when the COH oxygen is H-bonded, the νCO frequencies upshift to 1785−1800 cm−1. In double and multiple H-bond forms, H-bonding effects at individual sites are basically additive, and complexes in which the CO and the OH hydrogen are simultaneously H bonded exhibit ...
The DFT calculations were performed with the ADF program [70], [71], [72] using the OLYP exchange-correlation functional [73], [74] in conjunction with double- and triple-zeta polarized (DZP and TZP) Slater type basis sets (with TZP on the metal atoms and DZP on all other atoms) fr...
3o and 3p) in 85−95% yields; while the N-acyl-succinicimide 1of or N-acyl-glutarimide 1og counterparts required doubled-loading of dimethyl sulphate mediate and extended reaction time (24 hours) to achieve satisfactory reaction out comes in 85 − 88% yields. In addition, ...
In addition, on exploring the double electronic effects of the substituent on IP, the products 4m and 4n were also achieved in good yields. Encouraged by the results obtained from the selenylation of IP, we applied this transformation to the IP 1o, which is the core for a commercially ...