Bulk RNA-seqPeripheral bloodKey genesBACKGROUND Ulcerative colitis(UC)is a complicated disease caused by the interaction between genetic and environmental factors that affects mucosal homeostasis and triggers an inappropriate immune response.Single-cell RNA sequencing(scRNA-seq)can be used to rapidly ...
Current developments on single cell (sc) RNASeq technologies have given rise to sc-eQTLs, an approach that, although promising, is still bound to a limited number of individuals, which thereby limits the number of detectable cell type inter- action (CTi) eQTLs. Nevertheless, the ability to ...
Current developments on single cell (sc) RNASeq technologies have given rise to sc-eQTLs, an approach that, although promising, is still bound to a limited number of individuals, which thereby limits the number of detectable cell type inter- action (CTi) eQTLs. Nevertheless, the ability to ...
RNA-seq expression values were used as input to iSortTM Fractions to deconvolve 22 immune subsets in each sample.Results: Across 7 major populations, cell type fractions determined by iSortTM Fractions were highly concordant with ground truth fractions determined by clinical grade standards (r鈮 ...