Methods: We analysed the data on 257 362 women diagnosed with breast cancer during 2000–7 and registered in 13 population- based cancer registries in Australia, Canada, Denmark, Norway, Sweden and the UK. Flexible parametric hazard models were used to estimate net survival and the excess ...
Breast cancer frequently metastasizes to the skeleton, interrupting the normal bone remodeling process and causing bone degradation. Osteolytic lesions are the end result of osteoclast activity; however, osteoclast differentiation and activation are mediated by osteoblast production of RANKL (receptor activat...
Breast cancer is when the cells under one or both breasts grow out of control. Those cells may spread beyond your breasts. When that happens, the cancer is called metastatic. Did You Know? Different types of breast cancer grow and spread at different rates. Some take years to spread beyond...
ContextPhysical activity has been shown to decrease the incidence of breast cancer, but the effect on recurrence or survival after a breast cancer
SurvivalPrognostic factorsMetastatic breast cancer (MBC) remains an incurable disease, despite major advances in the treatment in the past 1012 years. Data on real life overall survival in a non-selected group containing all metastatic breast cancer patients are hard to find in the literature, as ...
Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer. PURPOSE: This study was performed to disclose the clinical impact of isolated tumor cell (ITC) detection in bone marrow (BM) in breast cancer. PATIENTS AND... Wiedswang,G. - 《Journal of ...
1.1 Triple negative breast cancer Triple negative breast cancer (TNBC) is aggressive, metastatic and a remarkable drug-resistant subtype of breast cancers [1]. It is the most challenging subtype due to the dearth of specific targets. Worldwide, TNBC is rising and accounts for nearly...
The 5-year overall survival rate is also lower for men (77.6%) when compared to women (86.4%) [12]. Albeit studies remain scarce, the same discrepancy is observed for transgender male to female, where breast cancer is usually diagnosed at a younger age 51.5-year old while the incidence ...
ContextSoy foods are rich in isoflavones, a major group of phytoestrogens that have been hypothesized to reduce the risk of breast cancer. However, the
Breast cancer, the most frequent female malignancy, is often curable when detected at an early stage. The treatment of metastatic breast cancer is more challenging and may be unresponsive to conventional therapy. Immunotherapy is crucial for treating met