The natural history of breast cancer remains controversial. It is unclear whether metastasis has already occurred by the time of presentation, especially in the caseof small, screen-detected tumours. The commonest sites of distant metastasis are bone, liver and lungs. Bonymetastases are commonest ...
Here, we discuss the molecular basis of breast cancer metastasis and the challenges in personalization of treatment. The instability of metastatic tumors remains a leading obstacle to personalization, because information from a patient's primary tumor may not accurately reflect the metastasis, and one ...
Cancer metastasis is a complex, multistage process, which eventually causes tumor cells to colonize and grow at the metastatic site16. Exosomes derived from tumors and stromal cells have been involved in all stages of cancer metastasis. In addition to the different types of substances loaded in ex...
Breast cancer metastasis accounts for the majority of deaths from breast cancer. Detection of breast cancer metastasis at the earliest stage is important for the management and prediction of breast cancer progression. Emerging techniques using the analysis of circulating tumor cells show promising results...
Although metastatic breast cancer is the most common maternal malignancy during the reproductive years, maternal melanoma is most likely to result in metastasis through the placenta to the fetus.93 Leukemia and adenocarcinoma at other sites (e.g., lung, colon) are also seen.94,95 View c...
Invasive breast cancer tends to metastasize to lymph nodes and systemic sites. The management of metastasis has evolved by focusing on controlling the grow
New molecular insights challenge the traditional model of metastasis, and indicate that the metastatic capacity of breast tumours is an inherent feature, and not necessarily a late, acquired phenotype. Local breast cancer might have a 'non-metastatic, good-prognosis' stem cell of origin; metastasizin...
Aim: Method: This research presents a model combining machine learning (ML) techniques and eXplainable artificial intelligence (XAI) to predict breast cancer (BC) metastasis and reveal important genomic biomarkers in metastasis patients. Method: A total of 98 primary BC samples was analyzed, comprisin...
Breast Cancer Research is the highest ranking breast cancer-specific title in the top quartile of oncology journals worldwide. Primarily publishing original ...
Breast cancer metastasis to the stomach resembling small benign gastric polyps A 60-year-old woman was admitted with abdominal distension. Ten years prior, she had been treated for breast cancer (lobular carcinoma; pTlc, G2, pNl bi, p... FL Dumoulin,RS Gupta - 《Gastrointestinal Endoscopy》 ...