The article explains the term "brainbow" as it relates to a Harvard research experiment on mice. Brainbow is used to describe the 160 different colored neurons in the brain of a mouse. Harvard scientists, led by Jeff Lichtman, used florescent proteins to change the color of neurons in mice'...
In the Brainbow mice from which these images were taken, up to ~160 colours were observed as a result of the co-integration of several tandem copies of the transgene into the mouse genome and the independent recombination of each by Cre recombinase. The images were obtained by the ...
In 'Brainbow' transgenic mice, nerve cells randomly express fluorescent proteins of different colors. Combinations of these proteins label neurons with multiple distinct hues, as seen here neurons of the hippocampus (confocal microscopy, dentate gyrus). (Image credit: Livet et al. Nature 1st Nov ...
Overall, UFObow can be crossed with different cell-specific Cre mice to precisely label specific cell types in different organs with great color complexity and labeling specificity, providing a universal means to track multiple cells of a specific type ex vivo and in living mice. UFObow enables ...
16 for labelling neuronal circuitry in Cre-expressing transgenic mice15,16. We inserted the Brainbow 1.0L cassette into the gG gene in the PRV Bartha genome by homologous recombination producing the strain PRV263 (for details see Methods). When PRV263 infects a Cre-expressing cell, Cre-...
The article explains the term "brainbow" as it relates to a Harvard research experiment on mice. Brainbow is used to describe the 160 different colored neurons in the brain of a mouse. Harvard scientists, lead by Jeff Lichtman, used florescent proteins to change the color of neurons in mice...
The article explains the term "brainbow" as it relates to a Harvard research experiment on mice. Brainbow is used to describe the 160 different colored neurons in the brain of a mouse. Harvard scientists, led by Jeff Lichtman, used florescent proteins to change the color of neurons in mice'...
The article explains the term "brainbow" as it relates to a Harvard research experiment on mice. Brainbow is used to describe the 160 different colored neurons in the brain of a mouse. Harvard scientists, led by Jeff Lichtman, used florescent proteins to change the color of neurons in mice'...
Definition brane-bo n: Name coined for the brain of a mouse that researchers bred to have neurons light up in 160 colors.rncontext Harvard scientists have raised mice whose genes contain fluorescent proteins (derived from coral and jellyfish) ...
Rac1 selective activation promotes axonal regeneration after optic nerve crush in Brainbow mice.Erika, LorenzettoMichele, EttorreValeria, PontelliMatteo, BolominiVittoriSilvia, BologninSimone, ZorzanCarlo, LaudannaMario, Buffelli