This chapter discusses that the brain is a cholesterol-rich organ, and increasing evidence suggests that cholesterol plays a number of key roles in the central nervous system (CNS) through regulation of membrane functions and by other mechanisms. Cholesterol metabolism in the brain makes special is...
Cholesterol is also a precursor of bile acids, and the precursor of all steroid hormones. The human brain is the most cholesterol-rich organ of the human body, despite occupying only 2% of body mass. Almost 25% of the total unesterified cholesterol of the total body is located there. ...
Balancing your blood pressure and cholesterol levels within a healthy range is vital to promoting brain health. 2. Manage blood sugar levels When we eat carbohydrate-rich foods, the stomach breaks it down into sugar (referred to as glucose). Our bodies then take up this glucose into our ...
In this review, we focus on the most well studied lipid—cholesterol. Brain is the most cholesterol-rich organ, it contains about 20% of the whole body's cholesterol (Björkhem et al., 2004). Unesterified cholesterol is the major sterol in the adult brain, and small amounts of ...
Much of the content of the human head is brain matter. This functions as the epicenter of human physical existence, including a sense of well-being and the manifestation of human consciousness. The human brain is a precious and complex organ which increases from 350 to 400 g in infants to ...
As the plasma membrane is enriched in cholesterol, the CNS composed of numerous neural cells with wide plasma membrane is a cholesterol- rich organ. Because inhibition of cholesterol supply induces cell death into neurons, the CNS is also an organ to highly require cholesterol. It is known that...
brain pericytes; TNFα; cholesterol metabolism; ABCA1; LXR; ABCB11. Introduction The brain is the most cholesterol-rich organ of the body and central nervous system (CNS) cholesterol synthesis accounts for the highest production rates across the body [1]. Cholesterol is an essential component ...
Physical examination is very helpful in trying to localize a potential brain lesion. A careful neurologic exam may be useful in finding weakness, changes in sensation (including light touch, pain, vibration, and position sense), and coordination. Mental status, agility, and other organ systems are...
The brain is a lipid-rich organ containing mostly complex polar phospholipids, sphingolipids, gangliosides and cholesterol. These lipids are involved in th... Sinclair,J Andrew,Begg,... - 《Asia Pacific Journal of Clinical Nutrition》 被引量: 211发表: 2007年 Can nutrients prevent or delay ons...
8a–d). A second fibroblast type (Fibro2) occupies the space between the leptomeningeal boundaries (Extended Data Fig. 8d) and is characterized by the expression of genes involved in the metabolism of glucose (G6PC)25, fatty acids (FABP3), cholesterol (SOAT1/2) and aromatic amino acids ...