BRAF mutation in metastatic colorectal cancer . N Engl J Med 361 : 98 – 99 .Tol J, Nagtegaal ID, Punt CJ: BRAF mutation in metastatic colorectal cancer. N Engl J Med 2009, 361(1):98-99.Tol J,Nagtegaal ID,Punt CJ. BRAF mutation in metastatic colorectal cancer.[J].The New England...
[25] Yungchang. C. et al., Phase Ib Study of Dabrafenib, Trametinib, Irinotecan and Cetuximab in BRAF V600E mutated Metastatic , Colorectal CancerJ Clin Oncol 41, 2023 (suppl 4; abstr 156). [27] Ben T. et al., Impact of BRAF mutation and microsatellite instability on the pattern of...
BRAF gene mutation in Iranian familial colorectal cancer patients at risk for Lynch syndrome Iranian Journal of Gastroenterology & Hepatology (GOVARESH)Zeinalian, MehrdadEmami, Mohammad HassanPourreza, Mohammad RezaTabatabaiefar, Mohammad AminHashemzadeh-Chaleshtori, Morteza...
Loss of SATB2 Expression in Colorectal Carcinoma is Associated With DNA Mismatch Repair Protein Deficiency and BRAF Mutation The special AT-rich sequence binding protein (SATB2) has been reported to be a specific immunohistochemical marker for colorectal carcinoma; however, corre... C Ma,DC Ol...
The objective of the study was to examine the role of microsatellite instability (MSI) and BRAFV600Emutation in colorectal cancer (CRC) by categorising patients into more detailed subtypes based on tumour characteristics. Tumour samples from 762 populati
结直肠癌组织EGFR、BRAF及NRAS基因突变检测及临床意义分析
1. Taieb, J. et al. Different prognostic values of KRAS exon 2 sub-mutations and BRAF V600E mutation in microsatellite stable (MSS) and unstable (MSI) stage III colon cancer: an ACCENT/IDEA pooled analysis of 7 ...
◆All patients with metastatic colorectal cancer should have tumor tissue genotyped for RAS (KRAS and NRAS) and BRAF mutations individually or aspart of an NGS panel. 所有转移性结直肠癌患者都应对肿瘤组织进行RAS(KRAS和NR...
[12] Samuel J K,et al. KRYSTAL-1: Updated Efficacy and Safety of Adagrasib (MRTX849) With or Without Cetuximab in Patients With Advanced Colorectal Cancer (CRC) Harboring a KRASG12C Mutation.2022ESMO LBA24. [13] ...
Discover all informations about the importance of mutation testing of the colorectal cancer. MAPK pathway, Outcomes and Biomaker testing.