Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and resorption by osteoclasts. These opposite processes allow the accommodation of bones to dynamic mechanical forces, altering bone mass in response to changin...
In our HCA model, new bone remodeling events are initiated over time at randomly selected locations such that multiple BMUs may be present at a given time as opposed to our previous HCA model27,40,41,42. We demonstrated that each BMU undergoes five key phases of bone remodeling: initiation,...
(99m)Tc-MIBI accumulation attributed to bone marrow metastases may occur at an early stage, before the bone remodeling process in the surrounding bone can be detected on conventional bone scans. 展开 关键词: bone marrow metastases bone metastases Tc-99m-MIBI scan Tc-99m-HMDP scan ...
However, when the balance is broken, that is, the function of osteoclasts is stronger than that of osteoblasts or the activity of osteoblasts is higher than osteoclasts, diseases such as osteoporosis and osteosclerosis may occur [88,89]. Moreover, in the process of bone remodeling, in ...
The crystalline texture and the collagen matrix are important parameters which point out the status of bone fragility and are predictors of the bone remodeling activity and fracture risk, by guiding the principles of therapy. 展开 年份: 2015 ...
During bone repair, a variety of processes need to be coordinated and these can be grouped in four different stages: the inflammation response, the formation of the soft and the hard callus and the remodeling of the bone (Fig.1) [18,19]. Inflammation, which is the initial stage in bone...
In general, multi events, such as blood clotting, inflammatory response, fibrocartilage callus formation, intramembranous and endochondral ossification, and bone remodeling are involved in the secondary bone fracture repair. Specific to the major metabolic activity, anabolism in a bone fracture is ...
The result of minimal trauma, a fall from no greater than the standing position or spontaneous vertebral fractures that may occur during normal daily activity without any apparent trauma. Periosteal surface The external or outer surface of bone. Medullary canal The central canal of a long bone, ...
are determinant factors of bone remodeling. They are greater when we move faster and/or more intensively, hence vary according to the type of physical activities6. Low impact sports such as swimming, can produce lower ground reaction forces than high impact sports such as gymnastics or cross-cou...
Iron metabolism plays crucial roles in bone remodeling, which is a complicated biological process.75Osteoclasts absorb bone tissue, whereas osteoblasts produce new bone tissue. To maintain bone integrity, this process must be tightly regulated. Increasing evidence indicates that both iron overload and ...