Zwaan FE, Hermans J, Lyklema A: Bone Marrow Transplantation for Leukemia in Europe: Factors Influencing the Possibility of Long-Term Leukemia-Free Survival. Exp Hematol (Supp1.17)13:3, 1985.Zwaan FE, Hermans J, Lyklema A: Bone marrow transplantation for leukemia in Europe: factors influencing...
Bone Marrow Transplantation for LeukemiaFor patients with leukemia, bone marrow transplantation provides a mechanism for avoiding the lethal consequences of marrow damage, making it possible to give "superlethal" chemoradiotherapy, and if...doi:10.1007/978-3-642-69934-4_2E. D. Thomas...
Bone marrow, soft, gelatinous tissue that fills the cavities of the bones. Bone marrow is either red or yellow, depending upon the preponderance of hematopoietic (red) or fatty (yellow) tissue. In humans the red bone marrow forms all of the blood cells w
SERIAL ASSESSMENT OF BONE MARROW (BM) COLONY FORMING CAPACITY (CFC) IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)In vitro semisolid agar culture has been used to characterize and predict relapse in myelold leukemias. We evaluated 5 children with ALL on the same drug regimen with ...
In leukemia, bone marrow transplantation is effecting cure in more and more types of leukemia and in different stages of the disease. This comprehensive review provides the reader with the background and rationale for transplantation, a description of the procedure itself and the potential ...
Between August 1985 and July 1994, we performed 115 volunteer unrelated donor (VUD) bone marrow transplants (BMT) for first chronic phase (n = 86) or advanced phase (n = 29) chronic myeloid leukemia (CML). Standard serologic HLA typing of potential donors and recipients was supplemented ...
Little is known about how leukemia cells alter the bone marrow (BM) niche to facilitate their own growth and evade chemotherapy. Here, we provide evidence that acute myeloid leukemia (AML) blasts remodel the BM niche into a leukemia growth-permissive and normal hematopoiesis-suppressive microenvironm...
Like normal hematopoietic stem cells, leukemic stem cells depend on their bone marrow (BM) microenvironment for survival, but the underlying mechanisms remain largely unknown. We have studied the contribution of nestin+ BM mesenchymal stem cells (BMSCs) to MLL-AF9-driven acute myeloid leukemia (AM...
Leukemia cells in the bone marrow must meet the biochemical demands of increased cell proliferation and also survive by continually adapting to fluctuations in nutrient and oxygen availability. Thus, targeting metabolic abnormalities in leukemia cells located in the bone marrow is a novel therapeutic app...
Bone Marrow Adipocytes Facilitate Fatty Acid Oxidation Activating AMPK and a Transcriptional Network Supporting Survival of Acute Monocytic Leukemia Cells 喜欢 0 阅读量: 25 摘要: Leukemia cells in the bone marrow must meet the bi 年份: 2017