Bone marrow-derived monocyte lineage cells (BM-MLCs) are im- portant angiogenic effector cells that produce a number of proangiogenic factors.13 The role played by proangiogenic BM-MLCs in hypoxia-induced retinal NV has been discussed mainly in the process of pathological NV.14 It has been ...
Int J Lab Hematol 30: pp. 349-364Lee SH, Erber WN, Porwit A, Tomonaga M, Peterson LC (2008) ICSH guidelines for the standardization of bone marrow specimens and reports. Int J Lab Haem 30:349–364Lee S.-H., Erber W. N., Porwit A., Tomonaga M., Peterson L. C. ICSH ...
Development of perfusion-based micro 3-D cell culture platform and its application for high throughput drug testing This study reports a new perfusion-based, micro three-dimensional (3-D) cell culture platform for drug testing using enabling microfluidic technologies. Th... MH Wu,SB Huang,Z Cui...
by 6 months of age, when recombination in LepR+cells was nearly complete, we observed virtually no nerve fibres in the bone marrow ofLeprcre/+; Ngffl/∆
It plays an important function in body support, tolerance of force damage and the protection of internal vital organs, as well as providing a stable circulation environment for the bone marrow [1,2,3,4]. Normally, bone has a certain regenerative potential over time in the face of minor ...
First, that myelodysplastic syndromes are highly proliferative disorders with almost one third of the marrow cells engaged in DNA synthesis (median LI for myeloid cells, 29%; median cell cycle time, 44 hours). Second, that unfortunately this high rate of cell birth is cancelled by an equally ...
Peripheral blood (PB) admixture should be minimized during numerical and functional, as well as cytokinetic analysis of bone marrow (BM) aspirates for research purposes. Therefore, purity assessment of the BM aspirate should be performed in advance. We investigated whether bone matrix vesicle (BMV...
Bone microvascular endothelial cells (BMECs) played an important role in the pathogenesis of glucocorticoid-induced osteonecrosis of femoral head (GCS-ONFH), and exosomes derived from bone marrow mesenchymal stem cells (BMSC-Exos) may provide an effectiv
(APCs) that generate all bone marrow adipose tissue (BMAT)26,28(Fig.2a). Given the increased bone formation in mutant females2, we reasoned that the brain-dependent osteoanabolic hormone might enhance ocSSC activity. OcSSCs from female WT mice were isolated by flow cytometry and transplanted ...
Bone marrow adipose tissue (MAT) is negatively associated with bone mass. Since osteoblasts and adipocytes are derived from the same precursor cells, adipocyte differentiation may occur at the expense of osteoblast differentiation. We used MAT-deficient KitW/W−v (MAT-) mice to determine if abse...