These results demonstrated that functional and metabolic regeneration of infarcted tissue could be realized in humans by bone marrow mononuclear cell transplantation27. Similarly, in the TOPCARE-AMI study28, 26 patients underwent bone marrow-derived cells transplantation after AMI, and first observations ...
Different from the gut microbiota results, antibiotics increased the community evenness and diversity of the oral microbiota (Fig.2b). Antibiotics also changed the composition (Fig.2a, c–d, S2c, d) and increased the pathogenicity of the oral microbiota. Bacteria associated with periodontal health ...
(1993) Bone marrow transplantation in Europe-can the geographical differences be explained?. Journal of Internal Medicine 233 :10.1111/joim.1993.233.issue-4, 311-313 /John M. Goldman. (1993) Bone marrow transplantation in Europe-can the geographical differences be explained?. Journal of Internal ...
The poor tolerance of irradiated bone marrow to chemotherapy may be explained in part by the ablation or suppression of certain marrow segments and also by the increased sensitivity of hyperactive, unexposed marrow. Because a greater proportion ofbone marrow stem cellsare cycling in the unexposed ...
bone marrow endothelial cellsand osteoblasts through activation of CD164 and αvβ2 integrin12–14. The high frequency of prostate cancer cell metastasis to bone, which occurs in virtually all patients, may be explained by the fact that these prostate cancer cells also bind to annexin-2, an ...
Several innate immunity genes are overexpressed in human cancers and their roles remain controversial. Bone marrow stromal antigen 2 (BST-2) is one such gene whose role in cancer is not clear. BST-2 is a unique innate immunity gene with both antiviral an
Patterns of bone breakage shed light on the intensity of mammal bone processing. This spectrum includes cut marks indicative of butchering and chopping, the extraction of marrow indicated by a spiral fracture, and the intensive pulverization of bones to render grease. Assemblage indicative of marrow...
The nuclear orphan receptor Nur77 (NR4A1, TR3, or NGFI-B) has been shown to modulate the inflammatory response of macrophages. To further elucidate the role of Nur77 in macrophage physiology, we compared the transcriptome of bone marrow-derived macrophag
2f). These data were further supported by the interaction between endogenous KDM4B and CCAR1 in bone marrow-derived macrophages (BMMs) (Fig. 2g). To more precisely determine the nature of the association between KDM4B and CCAR1, we performed additional co-IP experiments in cells expressing ...
In addition, higher concentrations of uremic toxin metabolites in the plasma and bone marrow of old mice were observed. The higher concentrations in the plasma of old mice suggest that they could be useful, non-invasive biomarkers of osteoporosis. The cross-validation of these uremic toxin ...