Colorectal cancerBone metastasis is rarely seen in colorectal cancer (CRC) patients, and there is insufficient data available regarding such cases. The study aimed to identify the prognostic factors and characteristics associated with overall survival in patients with bone metastatic CRC.#Data from bone...
In the current study, we aimed to identify risk factors associated with cancer prognosis and to detect the bone metastasis pattern of PCa patients in SEER database and a Chinese hospital. We compared the consistency and difference between SEER data and local hospital data. We were particularly in...
These are the master transcription factors of the Runx family of genes, the focus of this review, with emphasis placed on Runx2 that is abnormally expressed at very high levels in cancer cell lines that are metastatic to bone. Recent evidence has identified a correlation of Runx2 levels in ...
However, some patients did achieve fair and even good outcomes. We identified a variety of factors related to the patient, the initial thyroid tumor, and the sites and characteristics of the metastatic lesions that can serve for long-term outcome prognostication. Our study suggests the...
factors play important roles in the formation of the bone microenvironment for osteolytic bone metastasis in breast cancer [20]. The roles of miRNA-105 and miRNA-200 in extracellular vesicles produced by breast cancer in the pre-metastatic microenvironment still require further investigation [21,22,...
megaprosthesis; metastatic bone disease; surgery; complications; revision; sarcoma 1. Introduction Up to 70% of patients with advanced cancer present with long bone metastasis [1], and most of these patients will experience at least one skeletal-related event (SRE) in the form of pain or ...
bone, the survival rate drops to 39%-71%. Factors associated with a more favorable prognosis for Ewing sarcomas include smaller tumor size, age less than 10 years, having cancer in an arm or leg (instead of in the pelvis or chest wall), and having a good response to chemotherapy drugs....
In this study, we investigated precise blood biomarkers for evaluating BM that can improve the prognosis of patients with CRPC. Methods We comprehensively examined culture supernatants from four prostate cancer (PCa) cell lines using Orbitrap mass spectrometry to identify specific proteins secreted ...
Skeletal metastases in non-small cell lung cancer: a retrospective study. Lung cancer (Amsterdam Netherlands). 2007;57(2):229–32. Article PubMed Google Scholar Zhang G, Liu Z, Chen Y, Zhang Y. High serum HDGF levels are predictive of bone metastasis and unfavorable prognosis in Non-...
Varahram Shahryari1, Soichiro Yamamura1, Yuichiro Tanaka1, Gary Stein3, Rajvir Dahiya1 and Shahana Majid*,1 MicroRNAs (miRNAs) have emerged as key players in cancer progression and metastatic initiation yet their importance in regulating prostate cancer (PCa) metastasis to bone has begun to be...