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Lu等11提出了不同的观点,其发现接受2节段融合术的患者使用rhBMP-2可显著增加吞咽困难的严重程度,但不影响发生率,然而接受3节段或4节段融合术的患者发生率和严重程度与同种异体移植物组相似,对于接受4节段融合术的吸烟患者,使用rhBMP-2可降低假关节的发生率。...
本文是哥伦比亚大学Jianwen Que教授发表在Annual Review of Physiology题为“BMP Signaling in Development, Stem Cells, and Diseases of the Gastrointestinal Tract”骨形态发生蛋白(BMP)途径对消化系统多个器官的形态发生至关重要。BMP信号...
[2] Carragee E J, Hurwitz E L, Weiner B K. A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned[J]. Spine J, 2011, 11(6):471-91. [3] Spengler D M. Resetting standards for sponsored research: do co...
Sci Rep, 2021,11(1):22702. DOI: 10.1038/s41598-021-02100-w . 返回引文位置Google Scholar 百度学术 万方数据 [6] Lin HS , Liu Q , Zhao L ,et al. Circulating pulmonary-originated epithelial biomarkers for acute respiratory distress syndrome: a systematic review and meta-analysis[J]. Int...
在此基础上克隆了泰山赤鳞鱼BMP11的cDNA序列,并研究了此基因在不同胚胎发育时期及不同组织中的表达状况.从泰山赤鳞鱼的cDNA中扩增出一条643bp的条带,与斑马鱼的BMP11序列同源性高达92.34%,证明了此基因在不同物种间有高度的保守性.选择了11个不同的胚胎发育时期研究BMP11基因的表达规律,结果表明:BMP11基因在...
(BMP) signaling in the context of an inflammatory milieu. (6–12) Soft tissue injury can lead to increased expression of BMP4 (13) and other osteogenic cytokines, (11) as well as to induction of the BMP intracellular effectors, Smads 1 and 5,(14) providing a potential pathophysiological ...
我国台湾学者对海胆 BMP1 基因进行了克隆表达定位研究[11],结果显示 BMP1 基因 mRNA 和蛋白在囊胚期表达量最高,之 后会有所下降.在鸡胚胎发育过程中从原肠胚开始 有 BMP1 基因的表达,并持续性地表达于体节的形 成过程中[12].后来,Masafumi[13]克隆得到了小鼠 的 BMP1 基因的 cDNA 序列,并对其进行了分析...
International Journal of Molecular Sciences Review BMP Signalling at the Crossroad of Liver Fibrosis and Regeneration Blanca Herrera, Annalisa Addante and Aránzazu Sánchez * Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid (UCM), Health Research ...