BMP11C2C12 cellmyogenesislipid metabolismMuscle tissue influences energy and protein metabolism throughout the body. Earlier reports demonstrated that bone morphogenetic protein 11 (BMP11) could inhibit skeleton muscle proliferation and development. However, the role of BMP11 in the fatty acid metabolism ...
the molecular mechanisms are unknown. HIF-1a integrates the cellular response to both hypoxia and inflammation and is a prime candidate for regulating HEO. We investigated the role of hypoxia and HIF-1a in fibrodysplasia ossificans progressiva (FOP), ...
B. Bone morphogenetic proteins and articular cartilage: to serve and protect or a wolf in sheep clothing's? Osteoarthritis Cartilage 18, 735–741 (2010). Article CAS PubMed Google Scholar van der Kraan, P. M., Blaney Davidson, E. N. & van den Berg, W. B. A role for age-related...
- 《Mechanisms of Development》 被引量: 658发表: 1997年 The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient We have analyzed the role of mesoderm in the induction of the neural crest in Xenopus using expression of neural plate (Xsox-2) ...
BMP蛋白通路检测与Noggin蛋白活性检测 1.靶点和信号背景 （1）骨形态发生蛋白（Bone morphogenetic protein，BMP）是转化生长因子（transforming growth factor-β, TGF-β）超家族的一员。BMP在出生后骨的稳态包括成骨细胞增殖、分化和骨形成的过程中起着正性调节作用，是调节骨发育和骨代谢的最重要的因素之一[1]...
Bone morphogenetic protein (BMP) is a kind of classical multi-functional growth factor that plays a vital role in the formation and maintenance of bone, cartilage, muscle, blood vessels, and the regulation of adipogenesis and thermogenesis. However, understanding of the role of BMPs in antiviral...
Background:BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed ...
role ofBMPin stemcell biology 【J】.Oncogene,2005,24(37):5713-5721. 12 重庆医科大学硕士研究生学位论文 第一部分BMPl0、BMPl3和GFP的扩增及 C3H10Tl,2干细胞的感染 1材料与方法 1.1材料 1.1.1主要仪器 主要仪器名称 二氧化碳细胞孵养箱 台式离心机 ...
Role of miRNA-9 in Brain Development MicroRNAs (miRNAs) are a class of small regulatory RNAs involved in gene regulation. The regulation is effected by either translational inhibition or trans... B Radhakrishnan,AAP Anand - 《Journal of Experimental Neuroscience》 被引量: 2发表: 2017年 Homologies...
These mice not only form post-natal heterotopic ossification as occurs in human FOP, but also recapitulate the characteristic FOP great toe malformations and provide an in vivo model to investigate the role of Acvr1 signaling in skeletal development. Using these mice, we investigated the effect of...