BMP11C2C12 cellmyogenesislipid metabolismMuscle tissue influences energy and protein metabolism throughout the body. Earlier reports demonstrated that bone morphogenetic protein 11 (BMP11) could inhibit skeleton muscle proliferation and development. However, the role of BMP11 in the fatty acid metabolism ...
themolecular mechanismsare unknown. HIF-1a integrates the cellular response to both hypoxia and inflammation and is a prime candidate for regulating HEO. We investigated the role of hypoxia and HIF-1a in fibrodysplasia ossificans progressiva (FOP), the...
M., et al., Secreted BMP antagonists and their role in cancer and bone metastases. Bone, 2020. 137: p. 115455.6. Kang, H.W., R. Walvick, and A. Bogdanov, Jr., In vitro and In vivo imaging of antivasculogenesis induced by Noggin protein expression in human venous endothelial cells...
These mice not only form post-natal heterotopic ossification as occurs in human FOP, but also recapitulate the characteristic FOP great toe malformations and provide an in vivo model to investigate the role of Acvr1 signaling in skeletal development. Using these mice, we investigated the effect of...
B. Bone morphogenetic proteins and articular cartilage: to serve and protect or a wolf in sheep clothing's? Osteoarthritis Cartilage 18, 735–741 (2010). Article CAS PubMed Google Scholar van der Kraan, P. M., Blaney Davidson, E. N. & van den Berg, W. B. A role for age-related...
torsfamily,cantakepartincellproliferation,celldifferentiationandembryodevelopment.However,thestudiesonitsrolesinregen- erationarerelativelimited.Inthispaper,theBMPsignalpathwayanditsrolesinregenerationinseveralmodelanimalswereoutlined. ThispaperisattemptedtoprovideaninsightintostudyofrolesofBMPsignalingpathwayinregenerati...
1M). A similar trend was observed for Gsα protein expression in the TAC group (Fig. 1N). In summary, these results indicate that variations in Gsα expression were closely associated with the progression of TAC-induced HF and that Gsα may play a vital role in HF Cardiac-specific Gsα...
Using multiple genes in one organism has allowed us to determine whether FGF signaling is required for the induction of multiple early neural genes independent of BMP inhibition, and also to determine the role of FGF8a in neural development. Using gain and loss of function assays, we show that...
We report here the isolation and characterisation of three murine genes, Tlx-1, 2, and 3, which are related to HOX11 and con... SH Cheng,TW Mak - 《Development Growth & Regeneration》 被引量: 12发表: 1993年 Role of miRNA-9 in Brain Development MicroRNAs (miRNAs) are a class of ...
Role of TAK1 and TAB1 in BMP signaling in early Xenopus development Ectopic expression of Xenopus TAK1 (xTAK1) in early embryos induced cell death. Interestingly, however, concomitant overexpression of bcl-2 with the ... Shibuya,H. - 《Embo Journal》 被引量: 1231发表: 1998年 BMP-2, ...