Acute stroke causes complex, pathological, and systemic responses that have not been treatable by any single medication. In this study, using a murine transient middle cerebral artery occlusion stroke model, a novel therapeutic strategy is proposed, wher
We first tested whether a simplein vitromodel of the placental barrier would release a DNA damaging factor if it was exposed to agents that may cause leukaemia. A bilayered barrier of BeWo trophoblast cells resting on transwell inserts was used as the placental barrier model25,29. The top surf...
After washing, sections were labelled with goat-antimouse IgG (1:50) con- jugated to TRITC (Jackson), mounted in glycerine in phosphate buffer and viewed under a fluorescent microscope. Again, slides in which primary antibodies were omitted showed no vascular labelling whatsoever.Jocelyn A. Hola...
The blood–brain barrier (BBB) is a sophisticated structure whose full functionality is required for maintaining the executive functions of the central nervous system (CNS). Tight control of transport across the barrier means that most drugs, particularl
This increase in protein content parallels the change in size of dissected tissues observed under the stereomicroscope. This suggests there is increased flow of CSF through the ventricular system, which will be further enhanced by the concurrent increase in the rate of CSF secretion by the choroidal...
Fluorescence nanoscopy, also known as super-resolution microscopy, has transcended the conventional resolution barriers and enabled visualization of biological samples at nanometric resolutions. A series of super-resolution techniques have been developed
A study of immunogold-labelled blood group A erythrocytes in the scanning electron microscope.doi:10.1111/j.1600-0609.1988.tb00864.xH. E. HeierE. NamorkE. FallethBlackwell Publishing Ltd
E NamorkE FallethJohn Wiley & Sons, Ltd (10.1111)European Journal of HaematologyHeier HE, Namork E, Falleth E: A study of immunogold-labelled blood group A erythrocytes in the scanning electron microscope. Eur J Haematol. 1988;41: 17-24....
Recent research in artificial cell production holds promise for the development of delivery agents with therapeutic effects akin to real cells. To succeed in these applications, these systems need to survive the circulatory conditions. In this review we
(Electron Microscopy Services). After making the smear of whole blood and its separated components (RBCs and WBCs), the cells were fixed and stained using Wright-Giemsa stain for 5 min. The glass slide is then washed in DI water carefully and dried for observation under the microscope. ...