an electrical current is used to separate the different types of hemoglobin and thus detect abnormal hemoglobin. Testing a drop of blood by electrophoresis is helpful but may be inconclusive, especially for alpha-thalassemia. Therefore, the diagnosis is usually based on genetic tests and determination...
an electrical current is used to separate the different types of hemoglobin and thus detect abnormal hemoglobin. Testing a drop of blood by electrophoresis is helpful but may be inconclusive, especially for alpha-thalassemia. Therefore, the diagnosis is usually based on genetic tests and determination...
et al. Hb Bart's levels in cord blood and alpha-thalassemia mutations in Cyprus. Hemoglobin 24, 171-180 (2000).Kyriacou K, Kyrri A, Kalogirou E, Vasiliades Ph, Angastiniotis M, Ioannou PA, Kleanthous M. Hb Bart's levels in cord blood and α-thalassemia in Cyprus. Hemoglobin 2000;...
alpha] thalassemiagene mappinghemoglobinmean corpuscular hemoglobinhemoglobin EpgApplication of the technique of gene mapping has made possible accurate assessment of the defect in cord blood samples obtained in a Sydney teaching hospital. Results showed a 5.2% incidence of the haplotype in the population...
Alpha thalassemia has the two subtypes hemoglobin H and hydrops fetalis. Hemoglobin H is developed when a patient is missing up to three alpha globin genes or has mutations in up to these alpha globin genes. Complications from this disease can cause bone issues where the cheeks, forehead, and...
The results suggested that using cord blood electrophoresis to screen alpha thalassemia is prompt and accurate. It favors hereditary consultation, marriage guidance and prepotency.关键词: Newborn Cord blood screen Alpha-thalassemia 被引量: 1
alpha-thalassemia in the United Arab Emirates. A neonatal screening survey of alpha-thalassemia (alpha-thal) among the United Arab Emirates (UAE) nationals was conducted on 418 consecutive cord blood sa... S El-Kalla,E Baysal - 《Acta Haematologica》 被引量: 168发表: 1998年 ...
Alpha-thalassemia is caused by deletions of one or more of the four alpha chain genes on chromosome 16, with disease severity corresponding to the number of deleted loci. Beta-thalassemia is caused by mutations in the beta globin gene on chromosome 11. Delta–beta-thalassemia is caused by ...
Single-tube multiplex-PCR screen for common deletional determinants of alpha-thalassemia. Blood 2000; 95: 360–362. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative...
Arginase 1 is released during hemolysis and elevated levels have been described in hemolytic diseases, such as sickle cell disease and thalassemia. Furthermore, it has been shown to be associated with the severity of disease [5] as reflected by cardiovascular dysfunction and pulmonary hypertension [...