因此，集萃药康的BKS-db-eNOS KO小鼠模型对于糖肾疾病新药的非临床评价而言，无疑是一个理想的选择。关于集萃药康 江苏集萃药康生物科技股份有限公司，成立于2017年，是一家集实验动物小鼠模型的研发、生产、销售及技术服务为一体的高新技术企业。作为亚洲小鼠突变和资源联盟的重要成员，以及科技部国家遗传工程小鼠资源...
从糖尿病自发性突变(Lepr/db)纯合子小鼠肝脏分离出肝窦内皮细胞,表现为病理性肥胖、慢性高血糖、胰腺细胞萎缩和降血脂症。BKS db小鼠肝窦内皮细胞培养于T25组织培养瓶中,预先包覆以明胶为基础的溶液,培养2 min,在AcceGen’s culture Complete Growth Medium中培养,一般扩增培养3-7天。在运输之前,第3代的细胞从培...
BKS db小鼠脾内皮细胞是从糖尿病自然突变纯合子小鼠脾脏中分离出来的,表现为病态肥胖、慢性高血糖、胰腺β细胞萎缩和低血供。BKS db小鼠脾内皮细胞培养于T25组织培养瓶中,预先包覆明胶溶液2 min,在AcceGen特殊完全培养基中培养3-7天。在运输之前,第3代的细胞从细胞瓶中分离出来,立即冷冻保存在小瓶中。每毫升每瓶...
[2] Teixeira S R , Tappenden K A , Erdman J W .Altering dietary protein type and quantity reduces urinary albumin excretion without affecting plasma glucose concentrations in BKS.cg-m +Lepr db/+Lepr db (db/db) mice.[J].Journal of Nutrition, 2003, 133(3):673-678.DOI:10.1016/0014-5793...
BKS-DB miceSmall intestinal floraDGGEThe huge microbial communities play an important role in human physiology. More and more data shows that the intestinal flora, especially small intestinal flora, is closely related to metabolic disease, such as obesity and diabetes. In...
“Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice.” Cell 84.3 (1996): 491-495. 2.Yoon, Ji-Won, et al. “Genetic control of organ-reactive autoantibody production in mice by obesity (ob) diabetes (db) ...
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In addition, thymocytes from STAP-2/BKS-deficient mice showed the enhanced interleukin-2-dependent cell growth. Taken together, STAP-2/BKS is an additional modulator of STAT5-mediated signaling.Journal of Biological Chemistry
Composition of STAP-2; Induction of STAP-2 in mice liver in response to lipopolysaccharide; Regulatory role of STAP-2 in the acute-phase response in systemic inflammation.MinoguchiMayuShigeruAkiDaisukeJooAkikoYamamotoTetsuyaYumiokaEBSCO_AspJournal of Biological Chemistry...
价格:¥询价 规格: 1 vial 数量:-+ 产品描述 参考文献 资料下载 相关产品 产品描述/Products Description BKS db Mouse Vein Endothelial Cells are isolated from the vein of Mice homozygous for the diabetes spontaneous mutation (Lepr/db) manifest morbid obesity, chronic hyperglycemia, pancreatic beta cell...