In this paper, Mutlu et al. identifies a STING degrader, AK59, which inhibits downstream cGAS/STING activity through STING degradation employing a HECT-domain E3 ligase HERC4 and proteasomal ubiquitination pathway. Merve Mutlu Isabel Schmidt ...
Actual 2024 AQA GCSE BIOLOGY 8461/1H Paper 1 Higher Tier Question Paper + Mark Schem Exams University of Nairobi Biology 64 pages 2024/2025 (6) ISYE 6501 Final Questions with Answers SP21 Exams Chamberlain College of Nursing Biology 60 pages ...
Source data are provided with this paper. Change history 01 December 2022 In the version of this article initially published online, the word “Biology” mistakenly appeared at the start of the first affiliation, which has been amended to read “Beijing Frontier Research Center for Biological ...
Authors must declare the use of generative AI in scientific writing upon submission of the paper. The following guidance refers only to the writing process, and not to the use of AI tools to analyse and draw insights from data as part of the research process: Generative AI and AI-assisted ...
4133 Accesses 1 Altmetric Explore all metrics Abstract This research focuses on BioScientist, a digital game-based, inquiry-based learning program embedded in the biology curriculum that develops inquiry skills in 8th-grade students. The aim of this paper is to demonstrate a combination of elements...
Writing a research paper on ethics is not an easy task, especially if you do not possess excellent writing skills and do not like to contemplate controversial questions. But an ethics course is obligatory in all higher education institutions, and students have to look for a way out and be cr...
Zero measurements in scRNA-seq data have two sources: biological and non-biological (Fig.1). While biological zeros carry meaningful information about cell states, non-biological zeros represent missing values artificially introduced during the generation of scRNA-seq data. In our paper, non-biologica...
, and fox . those tf motifs are also reported in the original paper to be closely related to hematopoietic stem and progenitor cells generation process (additional file 1 : fig. s3d). scdart integrates human hematopoiesis datasets and learns myeloid and lymphoid cell trajectories we applied sc...
Here's a free Whitepaper on the topic. Whitepaper Five Innovative Automation Strategies to Accelerate Cell Line Development Empower your lab with tools and strategies that will help you develop GMP-compliant cell lines faster and more effectively by Sartorius Biopharmaceutical p...
To visualize EGFR activity during F-Cell specification, we first visualized the expression of EGFR itself and observed higher levels in the F-Cell than epidermal cells (Extended Data Fig. 5a,b). We therefore monitored the expression of an argos (aos)-GFP reporter, which becomes upregulated in...