Gene expression inference with deep learning[github][paper] This deals with a specific prediction task, namely to predict the expression of specified target genes from a panel of about 1,000 pre-selected “landmark genes”. As the authors explain, gene expression levels are often highly correlate...
we adopt the following naming scheme for the spatial domains by assigning each domain in a specific resolution with a term ID “Domain_N1_N2”, where N1 represents the resolution level (i.e., the number of detected domains, the larger the higher resolution) and N2 represents the ID of spe...
5d). An enrichment analysis of the depleted interactors revealed that the decrease was more marked for 1ae in all categories, in line with its higher potency (Fig. 5e and Supplementary Data Table 2). Focusing on Mediator, we found that, among all its subunits, MED1 was the most ...
methods, or criteria used for the comparison or the neutrality of the authors, was assessed. The number of benchmark datasets varied greatly, with 2 benchmarks using only 1 dataset and 1 benchmark using thousands of simulated datasets (median = 8). Likewise, the number of methods...
plotHypercube.motifsMotif plot of feature acquisition probabilities at discrete orderingsfeaturenames=c("") (set of feature names),label.size=3 (size of feature labels),label.scheme="full" (feature labels every timestep, or more sparsely) ...
3907 Accesses 1 Altmetric Explore all metrics Abstract This research focuses on BioScientist, a digital game-based, inquiry-based learning program embedded in the biology curriculum that develops inquiry skills in 8th-grade students. The aim of this paper is to demonstrate a combination of elements...
possible to dissociate the outcomes in the progeny from the maternal or paternal lineage with this experimental setting. Nevertheless, if the breeding scheme also includes exposed male x naïve female mating pairs and the outcomes of their male offspring are described, then the paper met the ...
Fig. 1: Daxx loss alters the chromatin landscape and transcription in LT-HSCs.a, Overview scheme of haematopoiesis. ST-HSC, short-term haematopoietic stem cells; MegE, megakaryocyte-erythrocyte; MEP, megakaryocyte-erythrocyte progenitor; GM, granulocyte-monocyte. b...
Elongin is a heterotrimeric elongation factor for RNA polymerase (Pol) II transcription that is conserved among metazoa. Here, we report three cryo-EM structures of human Elongin bound to transcribing Pol II. The structures show that Elongin subunit ELOA
Zero measurements in scRNA-seq data have two sources: biological and non-biological (Fig.1). While biological zeros carry meaningful information about cell states, non-biological zeros represent missing values artificially introduced during the generation of scRNA-seq data. In our paper, non-biologica...