Gallus toll‐like receptor 21 (gTLR21)homology modelleucine‐rich repeat (LRR) motiftoll‐IL‐1 receptor (TIR) domainToll-like receptors (TLRs) are an important part of the innate immune system, acting as a firs
MAF amplification increases the risk of breast cancer (BCa) metastasis through mechanisms that are still poorly understood yet have important clinical implications. Oestrogen-receptor-positive (ER+) BCa requires oestrogen for both growth and metastasis, albeit by ill-known mechanisms. Here we integrate...
The transition zones of the squamous and columnar epithelia constitute hotspots for the emergence of cancer, often preceded by metaplasia, in which one epithelial type is replaced by another. It remains unclear how the epithelial spatial organization is
CD4+ T cells respond to either IL-10, IL-27, or IL-21 and acquire a Tr1 cell phenotype. IL-10, IL-27, and IL-21 promote STAT3 activation, and IL-27 promotes the pioneering factors IRF1 and BATF that prepare the Il10 locus for the binding of the transcriptional factors. The transcr...
产品名称:IL10Rβ 试剂盒价格 英文名称:Human IL10Rβ (Interleukin 10 Receptor Beta) ELISA Kit 品牌:Guyan Biology 货号:GOY-H0015 产品包装:盒装 性状:瓶装液体 规格:96T/48T 保存条件:2-8℃ 保存期限:6个月 运输条件:2-8℃低温运输,用干冰或者生物冰袋低温运输。
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, γδ T cells, natural killer (NK), and NKT cells. IL-22 mediates its effectsviaa heterodimeric transmembran...
Keywords antiviral apoptosis cancer innate immunity pathogenesis receptor tropism vaccine virulence virus History Viruses exact an enormous toll on the human population and are the single most important cause of infectious disease morbidity and mortality worldwide. Viral diseases in humans were first noted...
The pro-inflammatory and anti-inflammatory properties of TNF are largely segregated by the capacity of this cytokine to bind to TNF receptor 1 (TNFR1) and TNFR2, respectively. The anti-inflammatory effects of TNF are explained by its capacity to increase the proliferation, stability and suppressiv...
虽然在烟草中成功合成QS-21,但尚未在人体内验证其效果和安全性。 数据表格 数据资源获取方式 Transcriptome and genome sequence data for Q. saponaria (BioProject IDs PRJNA914309 & PRJNA914519) SRA accession numbers: SRR22829626-SRR22829649 Sequences of specific genes (CCL1, CCL2, etc.) GenBank accessi...
Unmapped reads represent a rich resource for the study of B and T cell receptor repertoires and the human microbiome system—without incurring the expense of additional targeted sequencing. Studies of B and T cell repertoires produce results key to understanding the response of adaptive immunity ...