We work with conservation organisations across the UK to protect threatened wildlife. Collection We work with leading zoos and wildlife parks to collect biological samples from endangered animals. After an animal passes, or during routine veterinary procedures such as castration, we work alongside vete...
Here, we present an ensemble machine-learning framework (machine learning with phenotype associations, MILTON) utilizing a range of biomarkers to predict 3,213 diseases in the UK Biobank. Leveraging the UK Biobank's longitudinal health record data, MILTON predicts incident disease cases undiagnosed at...
The UK Biobank (UKB)3documents phenotypic variation of 500,000 participants across the UK, with a healthy volunteer bias4. The UKB whole-genome sequencing (WGS) consortium is sequencing the whole genomes of all the participants to an average depth of at least 23.5×. Here we report on the ...
providing the scientific community with a first-of-its-kind database that can be used to explore changes to an individual’s protein levels over mid-to-late life, with the potential to transform disease understanding, diagnostics and therapeutics. The UK Biobank is a large-scale biomedical datab...
Other efforts to elicit the attitudes of such stakeholders toward biobanks have been performed in the UK [32] and the Netherlands [33]. However, long- term financial sustainability cannot be achieved by apply- ing user fees alone. Biobanks should apply a holistic approach by relying on mixed...
However, little is known about the attitudes of medical researchers who use biobanks for research to these issues. Four focus groups with medical researchers in the UK were conducted in 2010–2011. The study highlights a range of issues associated with the research oversight and consent process ...
An example of one of the largest and most comprehensive worldwide biobanks is the UK biobank, a large-scale biomedical database and research resource, containing in-depth genetic, imaging studies and health information from half a million UK participants [44]. It is worth mentioning two register...
Stephen Quake, head of science at CZI, said: “The UK Biobank Repeat Imaging Project is a unique opportunity to measure human biology in action and to advance our understanding of the human body in health and disease. The Chan Zuckerberg Initiative is proud to support the creation of this la...
Biobanks contain biological samples and associated information that are essential raw materials for advancement of biotechnology, human health, and research and development in life sciences. Population-based and disease-oriented biobanks are major biobank formats to establish the disease relevance of human...
Nevertheless, the ideals of post-war solidarity have powerfully shaped the political and historical landscape of modern Britain and remain deeply embedded in contemporary culture. 10. In remarks made on the launch of UK Biobank its new Chief Executive, John Newton, referred to donated blood as ...