Bile acid biosynthesis: The metabolism of 7α-hydroxy-4-cholesten-3-one in the bile fistula ratBileAnimalsRatsBile Acids and SaltsCholic AcidsChenodeoxycholic AcidCholestenesCholestenonesCholesterolTime FactorsThe two primary bile acids, cholic acid (3α,7α,12α-tri-hydroxy-5β-cholan-24-oic ...
翻译 bileacidbiosynthesis 翻译 胆汁酸生物合成 以上结果来自机器翻译。 释义
et al. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102, 731–744 (2000). Article CAS PubMed Google Scholar Sanyal, S. et al. Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis....
Y. Bile acid signaling in metabolic disease and drug therapy. Pharmacol. Rev. 66, 948–983 (2014). Article CAS PubMed PubMed Central Google Scholar Holt, J. A. et al. Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis. Genes Dev...
potential for these molecules as endogenous biomarkers of liver disease andinjuryis discussed. Finally, the flatbile saltsfound in humans are compared to the ancestral and evolutionary older bile salts, which similarly have a flat steroidal structure, as mechanisms of flat bile acidbiosynthesisare ...
NIH 1989F32 GM Molecular Cloning of Bile Acid Biosynthesis GenesJelinek, Diane F. / University of Texas Sw Medical Center Dallas NIH 1988F32 GM Molecular Cloning of Bile Acid Biosynthesis GenesJelinek, Diane F. / University of Texas Sw Medical Center Dallas Comments Be the first to commen...
Bile acid biosynthesis The excess of free cholesterol is toxic to cells and needs to be excreted, primarily through conversion to more polar BAs. The introduction of a hydroxyl group in cholesterol reduces the half-life and directs the oxidized molecule to excretion [12]. BA synthesis is thus...
et al. Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis. Genes Dev. 17, 1581–1591 (2003). Article CAS PubMed PubMed Central Google Scholar Nicholes, K. et al. A mouse model of hepatocellular carcinoma: ectopic expression of ...
1. Increase of bile acid biosynthesis enhances the expression and activity of D-bifunctional protein in rat liver; 大鼠胆汁酸合成加强时肝D-双功能蛋白mRNA表达及活性升高2. Objective To determine the physiological role of D-bifunctional protein(DBP)in bile acid biosynthesis through investigating the ...
Feedback regulation of bile acid biosynthesis in the rat. The hepatic biosynthesis of bile salts in the rat has been shown to be controlled homeostatically by the quantity of bile salt returning to the liver via t... S Shefer,S Hauser,I Bekersky,... - 《Journal of Lipid Research》 被...